Genomic analysis of thousands of tumors supports new cancer classification
The Genetics of Cancer
CANCER GENETICS & EPIGENETICS
COMMENTS
Cancer genetics
Cancer genetics articles from across Nature Portfolio. Atom; RSS Feed; Definition. Cancer genetics is the study in humans and other animals of heritable gene variants that cause or confer altered ...
Cancer genetics, precision prevention and a call to action
This premise has been a central philosophy in the application of genetic testing for mutations in the cancer susceptibility genes (CSGs) that is now common place in family cancer clinics. Since most cancers have a significant heritable component 14 , there is now interest in the potential of genetic risk profiling to deliver personalised ...
Mutational landscape of cancer-driver genes across human cancers
The genetic mutations that contribute to the transformation of healthy cells into cancerous cells have been the subject of extensive research. The molecular aberrations that lead to cancer ...
Cancer Genetics
Cancer Genetics. Douglas W. Green, Jeffrey A. Drebin, in Surgical Research, 2001 I. Introduction Cancer is a disorder of cellular growth resulting from the sequential accumulation of genetic alterations in a clonal population of cells.
Cancer genetics
Cancer genetics articles within Nature Reviews ... CRISPR systems have enabled important advances in cancer research by accelerating the development of study models or as a tool in genetic ...
Epigenetic Determinants of Cancer
Cancer Genome Atlas Research Network. 2013a. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 499: 43-49. [PMC free article] [Google Scholar] Cancer Genome Atlas Research Network. 2013b. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 368: 2059-2074.
The Panorama of Cancer Genetics
Cancer risk arises from a combination of heritable genetic variants, often tagged by single-nucleotide polymorphisms (SNPs), and acquired somatic mutations. Genome-wide association studies (GWAS) have revealed many of the heritable variants, and tumor sequencing studies have identified many somatic drivers classified broadly as oncogenes and ...
Genetics of Cancer: Past, Present and Future
The research in cancer genetics in the past few decades has indicated an essential role of epigenetic modifications in the origin of a cancer and subsequent progression. The mutations in histones, the modification in histones involving methylation, acetylation, etc., and role of micro-RNAs and long noncoding RNAs, and changes in architecture of ...
Cancer Genetics and Clinical Research
Cancer is defined as a genetic disease because it is caused by mutations in genes which control cell grow and proliferation mechanisms . Yet, cancer is hereditary only when there is a specific oncogenic mutation inherited from previous generations. However, a lot of genes identified in familiar cancer syndromes have a role also in sporadic type ...
Editorial: Insight in cancer genetics: 2022
The articles included in this Research Topic "Insight in Cancer Genetics: 2022" have exploited these novel technologies to search for the genetic determinants of tumor development and progression of four different cancer types: breast cancer, acute leukemia, colorectal adenocarcinoma and hepatocellular carcinoma. ...
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COMMENTS
Cancer genetics articles from across Nature Portfolio. Atom; RSS Feed; Definition. Cancer genetics is the study in humans and other animals of heritable gene variants that cause or confer altered ...
This premise has been a central philosophy in the application of genetic testing for mutations in the cancer susceptibility genes (CSGs) that is now common place in family cancer clinics. Since most cancers have a significant heritable component 14 , there is now interest in the potential of genetic risk profiling to deliver personalised ...
The genetic mutations that contribute to the transformation of healthy cells into cancerous cells have been the subject of extensive research. The molecular aberrations that lead to cancer ...
Cancer Genetics. Douglas W. Green, Jeffrey A. Drebin, in Surgical Research, 2001 I. Introduction Cancer is a disorder of cellular growth resulting from the sequential accumulation of genetic alterations in a clonal population of cells.
Cancer genetics articles within Nature Reviews ... CRISPR systems have enabled important advances in cancer research by accelerating the development of study models or as a tool in genetic ...
Cancer Genome Atlas Research Network. 2013a. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 499: 43-49. [PMC free article] [Google Scholar] Cancer Genome Atlas Research Network. 2013b. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 368: 2059-2074.
Cancer risk arises from a combination of heritable genetic variants, often tagged by single-nucleotide polymorphisms (SNPs), and acquired somatic mutations. Genome-wide association studies (GWAS) have revealed many of the heritable variants, and tumor sequencing studies have identified many somatic drivers classified broadly as oncogenes and ...
The research in cancer genetics in the past few decades has indicated an essential role of epigenetic modifications in the origin of a cancer and subsequent progression. The mutations in histones, the modification in histones involving methylation, acetylation, etc., and role of micro-RNAs and long noncoding RNAs, and changes in architecture of ...
Cancer is defined as a genetic disease because it is caused by mutations in genes which control cell grow and proliferation mechanisms . Yet, cancer is hereditary only when there is a specific oncogenic mutation inherited from previous generations. However, a lot of genes identified in familiar cancer syndromes have a role also in sporadic type ...
The articles included in this Research Topic "Insight in Cancer Genetics: 2022" have exploited these novel technologies to search for the genetic determinants of tumor development and progression of four different cancer types: breast cancer, acute leukemia, colorectal adenocarcinoma and hepatocellular carcinoma. ...