Author Services from Springer Nature EN

Scientific Editing

Brought to you by Springer Nature

Get expert in-depth editing and strategic advice on your manuscript, review article or grant proposal from a team of editors following the quality standards set by Nature Research. Scientific Editing includes a Gold English language edit, a developmental edit, a quality assurance edit and a summary report. We specialize in research papers, reviews and grant proposals within the natural sciences (medicine, biology, chemistry, physics and earth sciences) and engineering.

A Team-based Assessment of Your Manuscript’s Needs

Scientific Editing team members meet to identify priority issues in the manuscript and discuss how the priorities can be addressed. We leave comments about additional documents provided for editing, such as cover letters or responses to reviewers. We provide insights into how readers, peer reviewers, and journal editors might view your paper.

A Thorough Developmental Edit

A Substantive In-Depth Assessment of Your Scientific Manuscript  

Based on the priorities identified in the team meeting, experienced members of the Scientific Editing team examine the text in significant detail and provide the following:

  • Strategic developmental edits that will improve the structure and clarity of the logical argumentation, such as how well the implications of the work are highlighted
  • Incisive comments recommending further author revisions that will help you maximize your manuscript’s effectiveness.
  • Improved  English grammar  to ensure that your ideas are conveyed clearly

A Thorough Strategic Report

Customized to the Needs of Each Scientific Manuscript

Scientific Editing also includes a custom 3-6 page report that includes:

  • Explanations of the prioritized issues identified in your paper, how we addressed them and/or how you might be able to address them further.
  • Insights into how readers, peer reviewers, and journal editors might view your paper
  • Strategic advice for improving your writing in the future.
  • Comments about additional documents provided for editing, such as  cover letters  or responses to reviewers.

Continued Support after Scientific Editing

Trusted by Researchers and Universities to Help their Science Stand Out

  • After you have received Scientific Editing and have considered the advice and made changes, we provide one free language edit (for field-specific grammar, phrasing, and punctuation correction) within 6 months of the completion of the initial order.
  • You may also want to purchase  Manuscript Formatting  at this time; from our partners, AJE

scientific manuscript writing service

Download one of our sample files to see the types of suggestions and edits made by our Scientific Editors

Confidentiality Assured

We never show your paper to anyone so you can be confident that when you submit to a journal, the editor’s decision will be independent and fair

These policies relate specifically to Nature Research Editing Service. Please see also our  Terms of Service  for other core principles, for example regarding the confidentiality of your documents. Our aim is to serve the interests of authors and institutions, not the editorial and publishing interests of Springer Nature journals. We openly and clearly declare to potential and current customers that we are part of Springer Nature, and we inform potential customers about our independence from the publishing process. We aim to be publisher-neutral in our editing and advice, and especially in our journal recommendations (where applicable). We take steps during the editing process, when giving advice, and when recruiting and training editors to help us achieve this aim. Nature Research Editing Service does not measure its success in terms of the publication of edited documents by Springer Nature journals. We do not involve ourselves in the publishing process. We do not guarantee publication of papers or funding of grant applications. We expect journal editors and grant review panels will make these decisions entirely independently of Nature Research Editing Service and other author services providers. Draft journal articles and their scientific content are not shared with professional editors who make decisions on research papers at Springer Nature journals. Any comments that we make regarding the suitability of specific target journals are explicitly presented as opinion and not as a definitive prediction of the outcome of submission. If an author indicates that they mainly want to know whether or not their paper is acceptable to a specific Springer Nature journal, or has any other query for which a Springer Nature journal editor is the most appropriate contact, we will suggest that the author contacts the journal directly. We do not suggest peer reviewers. We do not infringe on authorship. When editing documents, wherever possible, we provide our edits and comments in an easily reviewable format. We encourage authors to review our input critically, rather than accepting all of our edits and suggestions without review. We never confirm that any document is ready for submission, submit anything to a journal or funding body, or correspond with journal editors or peer reviewers on behalf of authors. We do not ghostwrite or completely rewrite large passages of text, and we do not directly introduce ideas that are not already present in the documents submitted to us. Our editing focuses on improving how the existing research is communicated. General policies We do not engage in or encourage practices that contravene relevant ethical guidelines. For Scientific Editing, if we suspect unethical practice in a submitted document or correspondence, we will point it out and explain it. If we suspect severe infringement of ethical requirements or laws (particularly unacceptable harm to humans or animals), we act on this where possible. We review these policies on a regular basis and keep up-to-date with issues arising in the publication ethics landscape. We train editors to follow these policies, we monitor adherence to these policies, and we take action in the event of any failure to follow them.

Our Quality Guaranteed

To ensure that the changes you make based on the editor’s report are grammatically correct, we include one free language re-edit of your revised paper before you submit to the journal (for Scientific Editing only). To claim this free re-edit, email support within 6 months of your original order and attach your revised paper. After this free re-edit, we guarantee that if your language-edited paper is rejected by a journal because of the English alone, we will re-edit your paper once for free.

Where Our Customers Publish

  • Advanced Functional Materials
  • Cancer Research
  • Developmental Cell
  • Earth and Planetary Science Letters
  • Energy and Environmental Science
  • Genome Biology
  • Geophysical Research Letters
  • Journal of Experimental Medicine
  • Nano Letters
  • Nature Climate Change
  • Nature Communications
  • Nature Genetics
  • Nature Geoscience
  • Nature Medicine
  • Proceedings of the National Academy of Sciences of the United States
  • Science Advances

Testimonials

I would like to express my sincere appreciation for your work. You did really an excellent job. What I liked in particular was that you gave comments with substantial suggestions how to improve. Although I have published till now quite a number of scientific papers (>300) and many of them in high impact journals I learned a lot throughout this. I Iook forward to future cooperation of mutual benefit. -Full Professor · University of Bayreuth · Germany

The report with the feedback summarizing edits and comments is very informative. We appreciate a lot your editor’s work, with changes tracked and comments on the text improving clearly our manuscript. Finally, your recommendations concerning the most appropriate journal for publication will decidedly help us for the next submission of our manuscript. -Research Director, CNRS/Team Leader · Sorbonne University · France

Welcome to BMJ Author Services

  • 24/7 Service With A Reply In Minutes
  • 100% Satisfaction / Your Money Back

“The experience was very good and the premium editing was very helpful. Thank you!”

- Joanna Kowalska

BMJ partners with Editage to offer Author Services to Medical Researchers worldwide and assist them in their publication goals. Editage offers professional editing by specialized subject experts in Medicine . With a comprehensive quality guarantee, Editage promises to assist you until you are ready to submit.

Services we offer

  • English Editing Services
  • Translation Services

We offer four levels of manuscript editing services. Each service level differs in terms of the scope of edit and post-submission support. All four levels of editing include free manuscript formatting for the BMJ journal of your choice. This will save your time and budget.

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Plus Plan
Publication-focused editing that makes your manuscript ready for initial submission.
Select this service if you like the editor to help with extensive language revisions, organization of your article, and feedback on your writing. -->
Features
Features
Features
Revisions for grammar, terminology, word choice, & native English tone
Revisions for grammar, terminology, word choice, & native English tone
  Editing certificate (upon request)
Editing certificate (upon request)
  Letter From The Editor
Letter From The Editor Included in Scientific Review Report
  Unlimited Q&A with editor
Unlimited Q&A with editor
  Intensive edit for organization (rephrasing and restructuring)
Intensive edit for organization (rephrasing and restructuring)
  Customized cover letter
Customized cover letter
  Feedback on original writing
Feedback on original writing
  Unlimited re-edits for 365 days
Unlimited re-edits for 365 days 60% discount Free Free
  Word count reduction
Word count reduction Word reduction by 10% Word reduction by 20% Unrestricted
  Journal-specific formatting
Journal-specific formatting Free for one journal Free for one journal Free for multiple journals
  Journal response letter editing & cross-checking with the revised manuscript
Journal response letter editing & cross-checking with the revised manuscript
  Scientific Review Report which includes:
Scientific Review Report which includes:
  In-depth technical review by top-tier journal peer reviewer
In-depth technical review by top-tier journal peer reviewer
  High-quality developmental editing focusing on paper structure and research design
High-quality developmental editing focusing on paper structure and research design
  Journal submission readiness check by Managing Editor or senior editor
Journal submission readiness check by Managing Editor or senior editor
  Free plagiarism check report
Free plagiarism check report
 

Don’t get lost in translation! Our academic translators and editors offer subject-specific expertise and superior editing skills to ensure that your manuscript accurately conveys every nuance of your research in perfect scientific English to a global audience. Our aim is simple: deliver a manuscript that journal editors, reviewers and readers find indistinguishable from those written by native English speakers.

We offer subject-specific translation with English Editing for the following language pairs.

  • Traditional and Simplified Chinese to English
  • Spanish to English
  • Korean to English
  • Japanese to English
  • Brazilian Portuguese to English
  • Turkish to English

scientific manuscript writing service

Why choose BMJ Author Services?

Our goal is 100% client satisfaction. That is what we aim for in everything we do.

From the quality of our editing and translations to the timely delivery of your completed manuscript, we make sure you are satisfied with our service every step of the way.

You reach out to us for expert author services, and we mean to deliver. Our team will work with you until your expectations are met.

scientific manuscript writing service

  • Quality guarantee
  • Delivery guarantee
  • Confidentiality
  • Multiple payment options

Two-Editor Check

Each document is checked by two language specialists from our global team of editors and peer reviewers to ensure that we miss nothing. The end result will meet the highest quality standards of international journals.

RESPONSIVENESS

24-Hour Response Time

Whether you are sending in a submission or query, our customer support managers will respond to you within 24 hours, with solutions customized to your needs. If your document submission is even a second late, we offer a full fee refund, No questions asked!

CONFIDENTIALITY

128-bit SSL encryption

Our ISO/IEC 27001:2013 certified IT security management systems and processes ensures that researchers worldwide can submit their papers with complete confidence that their intellectual property is safe with us.

Easy, secure payment gateways

Pay via credit card

We accept Visa, MasterCard, American Express, Diners Club, and Discover, and have partnered with two payment gateways—PayPal and CC Avenue. The payment gateways available to you will differ depending on your country and the card you choose to use.

Pay via bank transfer

You can make payments directly into our bank account and email the bank wire transfer receipt to us. We recommend bank wire transfer for payments exceeding $1000.

Native English editors - specialists in your subject area guiding you to publication success

Our unique editor-selection algorithm ensures that your paper is assigned to highly qualified language specialists with expertise in your subject. As it learns your requirements, we are able to offer more tailored services. Our editors are all native English speakers who hold PhDs or Master’s degrees from top universities such as Harvard, MIT and Oxford. They are all experts in their respective academic fields with an average of 19.4 years’ experience in editing. Most of them are published authors and peer reviewers in their own right as well as members of some of the world’s best editor societies, such as BELS and CSE.

scientific manuscript writing service

  • Cardiology and Vascular Medicine
  • Biomedical Devices and Pediatrics
  • Organ Systems (Gastroenterology, Urology, etc.)
  • Muscle, Bone, and Physical and Sports Medicine
  • Plastic Surgery
  • Reproductive Medicine and OBGYN

scientific manuscript writing service

  • Radiotherapy Planning
  • Diabetes and Endocrine Research
  • Epidemiology

scientific manuscript writing service

  • Clinical Oncology
  • Biochemistry and Structural Biology
  • Systems Biology and Biostatistics
  • Molecular Biology: Embryonic, Cellular, and Evolutionary
  • Microbiology and Immunology

Publication Ethics

We at BMJ, and our partners at Editage, are aware of the increasing pressure that the academic research and publishing community are under today. As a leading provider of editorial and publication support services for the past 12 years, we have on occasion been witness to potential cases of ethical violation while editing research papers. A majority of these are instances of “accidental plagiarism” where authors unwittingly engage in unethical practices, mainly because of lack of information and professional training on the subject.

As the first people to look at research papers, even before journal editors do, we can serve as trusted advisors to thousands of researchers, especially early-career scientists not fully aware of the pitfalls of unethical academic publication by:

  • Ensuring quality
  • Offering processes for suspected ethical misconduct
  • Providing educational initiatives for editors and authors

Frequently asked questions

What are the different types of editing services you offer.

We provide manuscript editing services to meet the publication standards of international high-impact journals. We offer 3 levels of manuscript editing and proofreading services for academic research papers.

What training do your editors and writers receive?

All our manuscript editors and writers go through the Basic Editor Training (BET) program that comprises 5 standard modules and various customized programs.

Authors' success stories

“The unique and extremely helpful thing about Editage is its professionalism and punctuality! For non-native authors, Editage makes your writing language more academically and professionally. Thus more chance to getting publish.”

Poowin Bunyavejchewin Walailak University, School of Liberal Arts

It was great to have a native speaker scrutinize our manuscripts. We managed to publish two papers with the help of Editage in good quality international journals. I suggest using Editage to my colleagues to get a flawless manuscript before the publication.

Lukasz Kaczmarek Adam Mickiewicz University

It's really a high quality editing service and I'm quite pleased about the work. If an author is seeking qualified writing and publication support, this is really true address.

Ugur Erdemir Istanbul University, Assc. Prof., Dentistry

Get Published! AJE is the Preferred Editing Service of Nature Journals

We know how much effort goes into publishing a paper. Our team of advanced degree-holding experts provides English language editing, academic translation, and other manuscript preparation services, all backed by our 100% satisfaction guarantee.

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Trusted by the most respected names in scientific publishing

Reputation is important in the research community. World-class publishers like Springer Nature trust AJE to deliver high-quality English editing and manuscript preparation services to their authors.

journals and societies recommend AJE

field-specific topics in 400+ areas of study

authors served in 192 countries

AJE Success Stories

See where authors like you have been published after using aje editing services..

An Efficient Hybrid Particle Swarm Optimization Algorithm for Solving the Uncapacitated Continuous Location-Allocation Problem

a stack of academic journals

CA: A Cancer Journal for Clinicians

Impact Factor: 286.13

Game theory-based model for maximizing SSP utility in cognitive radio networks

New England Journal of Medicine

Impact factor: 176.079

The impact of pharmacological and non-pharmacological interventions to improve physical health outcomes in people with schizophrenia: a meta-review of meta-analyses of randomized controlled trials

World Psychiatry

Impact factor: 79.683

Enterobacter spp.: Update on Taxonomy, Clinical Aspects, and Emerging Antimicrobial Resistance

Clinical Microbiology Reviews

Impact factor: 50.129

The de Winter Electrocardiogram Pattern Evolving From Hyperacute T Waves

JAMA Internal Medicine

Impact factor: 44.409

Adrenocortical carcinoma - towards genomics guided clinical care

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Nature Reviews Endocrinology

Impact factor: 47.564

The highest quality English editing and translation

An AJE English editing expert editing a scientific manuscript

English Language Editing

Get a publication-quality version of your manuscript, abstract, thesis, grant, or academic book. In-house US-trained English-speaking editors will correct errors in spelling, grammar, word choice, scientific terminology, and phrasing.

Starting at $38

scientific manuscript writing service

Nature Research Scientific Editing

We’re partnering with Nature Research to offer our most in-depth and accurate evaluation and edits for your manuscript or grant. Scientific Editing includes a rigorous language edit, a developmental edit, a quality assurance edit, and a summary report.

Starting at $1500

scientific manuscript writing service

Translation with English Language Editing

We combine state-of-the-art AI technology with our in-house language experts to help speed up the process of getting reviewed and accepted in high-impact journals.

Starting at $149

Testimonials

Bruno Ricardo Barreto Pires

MD | ONCOLOGY

"I am very pleased with AJE's English editing service. I have used this service in all my publications, and I am excited to use it again. I can say that AJE's work is critical because the review identifies errors that are not obvious to those who have English as a second language. The team is accessible throughout the review process, has a high level of technicality and professionalism, so I acknowledge AJE's merit for significantly improving the quality of my manuscripts. I highly recommend their services"

Gangxiong Wu

PHD | ENGINEERING

"When I used to submit papers to SCI top journals (although I repeatedly modified them many times) I still worried about my English professional proficiency. I searched the Internet for a common English-language retouching service. After comparison, I found that AJE is the best. On the one hand, they are real native English speakers; in addition, they are fair and reasonable. They are also very professional and efficient. The editor carefully revised and changed my grammar and spelling mistakes in detail, and modified some of my expressions to make it more professional. After the revision, the paper was much smoother to read, and I learned a lot about writing in English. Sure enough, my paper was successfully accepted by top journal the first time I submitted with the help of AJE. I am especially grateful to the AJE team members for their help."

Meet the team of people invested in your success

Our highly-trained, in-house editors are experts in 447 areas of study and over 2000 field-specific topics. You can trust that the person working on your paper is not only an expert in English but also fluent in the language and conventions in your field. AJE editors bring years of experience to every order, and our commitment to quality is unparalleled. Select an area of study below to see more about how AJE can help with your specific field.

Clinical Medicine

Since 2004, we have supported authors like you on over 160,000 papers in the medical sciences and related subjects.

Life Sciences

Since 2004, we have supported authors like you on over 190,000 papers in the life sciences.

Physical Sciences

We have supported authors like you on over 90,000 papers in the physical sciences.

Business and Law

With experts in over 400 academic fields, AJE has helped authors publish papers about finance, entrepreneurship, criminal law, and tax law in high-impact journals.

Humanities and Social

AJE has helped authors publish papers about communications, public policy, education, and political science in high-impact journals.

Engineering and Materials

AJE has helped authors publish papers about robotics, biomaterials, metallurgy, and civil engineering in high-impact journals.

Mathematics and Computers

AJE has helped authors publish papers about logic, statistics, algebra, and topology in high-impact journals.

Supporting you in every phase of publishing

scientific manuscript writing service

Manuscript Formatting

Meet the formatting guidelines of your target journal: our team will modify your manuscript’s layout, headings, title, image placement, and citations/references to comply with your journal’s requirements.

Starting at $75

scientific manuscript writing service

Grant Services

Achieve success with your grant applications with clear communication that meets funder guidelines. We can polish your language and add customizable elements such as video, figures, and infographics to help grant reviewers see the potential in your grant proposal.

scientific manuscript writing service

Journal Recommendation

Get a detailed report and our top recommendations on where to submit your article, based on your topic, scope, impact, and publishing goals.

Starting at $150

Further assistance for researchers

Visit our AJE Scholar Author Resource Center for articles on preparing your manuscript, thesis, or grant.

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Get early access to aje scholar articles, discounts on aje services, and more., editing and translation services providing publication ready manuscripts.

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Enhanced manuscript quality

From draft to polished gem: Elevate your manuscript to its full potential. Improve clarity, coherence, and impact with AJE expert insights.

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Increased publication opportunities

Open doors to publishing success. Boost your submission confidence and attract editors' attention with a professional edge.

a researcher saving time on their manuscript by using AJE editing services

Time and energy savings

Reclaim your time and focus. Let us handle the editing, so you can create more. Free up your valuable time and energy to do what you love, while we polish your manuscript.

Draft to debut: your road to high-impact publishing success

Struggling to meet the high English language standards of academic journals, especially if English is not your first language?

Feeling overwhelmed by the complexities of the journal submission process?

Dreading the gauntlet of peer review and the daunting prospect of desk rejection?

Submitting a paper to a journal with higher impact factor?

AJE editors working on a clinical studies manuscript

Choose from four levels of English Editing

Your research deserves to be heard. Don't let publication roadblocks silence your voice. We offer solutions to overcome these challenges and get your work published in prestigious journals. Let us guide you through the process and amplify your research impact.

Additional services

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Curie refines your language and structure, helping you make a stronger case for your scientific findings. With improved writing, your work will stand out and make a lasting impact.

$11.25/monthly

A researcher using an AJE editor's suggestions from Presubmission Review

Presubmission Review

Our in-line commentary will help you improve the structure of your paper and ensure that your ideas are communicated clearly and accurately.

An AJE English editor after using the Grammar Check Tool

Grammar Check

Use our fast, free language assessment tool to check whether your communication is ready for submission.

AI software checking a researchers manuscript for plagiarism

Plagiarism Check

Our AI tool thoroughly checks your manuscript to ensure that no citations are missing, helping you avoid potential issues related to incomplete or inaccurate referencing.

We get it - securing publication can be hard

There are plenty of manuscript preparation services to choose from. but at aje, our editors, proficient not only in english but also in the language and conventions of your field, bring years of expertise to elevate the quality of your paper. trust in our unparalleled commitment to ensuring your work reaches its utmost potential with our academic editing..

After my first experience with AJE, my manuscript was accepted by a journal in Science Citation Expanded. I wholeheartedly recommend AJE.

researcher

M. Sirvanci

AJE's services are absolutely perfect for my needs - excellent American/English editing and the best grammatical constructions. My paper was revised in less than 48 hours, which is literally a DREAM for the fast moving brain of a scientist!

A. Proverbio

I'm from Inner Mongolia University, China and not very skilled at English. AJE's editors helped improve my grammar and sentence patterns. My article has been accepted for publication in the Letters in Applied Microbiology.

AJE's English Editing service is highly recommended for all high-quality research in biochemistry, medicinal chemistry, and virological drug research. Full compatibility with chemistry-containing articles in virology is certainly guaranteed with AJE.

A simple 3-step journey to publication success

an AJE editor editing a manuscript

1. Submit your manuscript

Share your groundbreaking work with us! It will be carefully matched with an AJE expert editor (link?) who specializes in your specific field. They'll understand the nuances of your research and the expectations of your target journals.

2 scientific editors editing a clinical studies manuscript

2. Get your edited manuscript

Dive deep into expert feedback delivered through a detailed report. Your AJE editor will meticulously polish your manuscript, addressing language clarity, sentence structure, flow, and academic conventions. This ensures your research shines its brightest.

An AJE editor going through the changes made to a researcher manuscript

3. Get published

Armed with confidence and a polished manuscript, submit your work to your dream journal with increased chances of success. Your research deserves to be heard, and we'll empower you to make it happen.

The AJE Guarantee

At AJE, we understand the challenges researchers face when striving for academic excellence. The intricacies of language editing and adherence to field-specific norms can create stress and hinder your progress. That's why we've developed comprehensive editing services tailored to your academic needs.

With AJE, you can leave the hassle of refining your manuscripts to us, allowing you to stay focused on your research and academic pursuits. Our expert editors, fluent not only in English but also in the language and conventions of your field, bring years of experience to ensure your papers meet the highest standards for publication.

Trust AJE to handle the intricacies of your academic writing, so you can concentrate on what you do best – advancing knowledge and making a significant impact in your field.

the AJE guarantee

Unlock your publishing potential with our free e-book: AJE Tips for Publication Success

Dreaming of seeing your research in top journals? Our comprehensive e-book empowers you to overcome common roadblocks and navigate the publishing process with confidence.

A walkthrough of each section of the manuscript with thorough highlights and tips.

Tips for navigating the publishing process from writing your cover letter, formatting your manuscript, and choosing a journal.

Advice for editing and translating your manuscript.

AJE Tips for Publication Success

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Scientific Editing and Writing Solutions at Clarity in Science

At Clarity in Science Editing and Writing, we understand the pressures of publishing high quality science in top journals, because we’re led by successful investigators ourselves.

Elevating Your Science, One Word at a Time

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You know your science is good – really good. You want to get it published in the best possible journal you can. But you could use some help making sure that you’ve expressed yourself well,

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Writing grants is perhaps the most challenging thing that successful scientist has to do. The pressure is high. You know that if you don’t bring in enough support,

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Sometimes you want more than just an edit. You are really busy. We understand. We’ve been there. If you have a paper that needs to be written but you just have not had the time to write.

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The difference between a sloppy figure and one that is really well made can be all the difference in the world in getting your manuscript accepted or your grant funded.

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Our mission is to provide the most sought-after scientific editing service for life scientists, oncologists, physicians, and others, contributing to the advancement of knowledge by helping the best investigations get published with the most effective, clear language.

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Pre-submission and Article Promotion services to support your publication

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Do you need help preparing your manuscript for submission to a journal and then promoting your published article to a wider audience? Taylor & Francis offers a full range of services to take care of tidying up your manuscript and maximizing impact so you can devote time to your research.

Our Services

English Language Editing

English Language Editing

Our English language editing services let you focus on what you do best – research. We review your manuscript to ensure the language you’ve used makes sense and is clear, and check for spelling, grammar, syntax, tense, and sentence structure.

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English Language Editing

Scientific Editing

Our Scientific Editing service is designed to offer you an in-depth critique of your research, significantly improve the readability of your paper, and help you ensure that your journal submission meets the high standards of academic publishing.

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Translation with Editing

We help you overcome any language barriers by translating your article into English and editing it thoroughly, so that you can submit it to an English-language journal with confidence.

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Manuscript Formatting

We make sure that your manuscript complies with your target journal’s Instructions for Authors. We use the utmost care to adhere to styles like APA, MLA, ACS, and AMA.

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Article Promotion Services

Promote your research with graphical abstracts, infographics, videos, research news summaries, and lay summaries. Our Article Promotion Services can raise public awareness of your work and engage peers, funders, and the media.

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An experienced reviewer panel could help you to eliminate most major reasons for manuscript rejection before submission. Get comprehensive comments that will help you revise your document and still meet publication deadlines.

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You can count on us for excellence, expertise, and responsiveness in all our services. If we don’t deliver, we will not charge you, no questions asked.

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Delivery guarantee

We guarantee that all assignments will be delivered on time. We will waive the full fee for any assignment that is delayed due to an error on our part.

Subject specialists

Subject specialists

Our unique editor-selection algorithm ensures that your article is assigned to highly qualified specialists with expertise in your subject; all our native English-speaking editors hold a PhD or Master's degree.

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Our privacy policy ensures confidentiality and allows researchers worldwide to submit their work to us with complete confidence.

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  I chose Taylor & Francis because they offered a range of services, affordable pricing, and a simple payment and submission process. The biggest benefit was receiving a well-edited manuscript with useful recommendations. I will recommend them and use Taylor & Francis again in the future  

Dr. Dmitry Gusarov

MGIMO University

  I chose Taylor & Francis Editing Services because they don't advertise constantly which, in my opinion, somehow shows credibility. I need a second opinion to check the clarity of my language so my writing represents my content properly. I picked Premium Editing Plus and did not regret it. I would opt for the same service again and would tell friends and colleagues about it.   

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Top Impact Scientific Editing starts with a rigorous examination by a working researcher in your field. They offer practical suggestions to improve your research presentation, drawing from their experience editing or reviewing for top journals like Nature , NEJM , and The Lancet .

• Assess structure, organization, and scientific argument • Ensure discussions and conclusions address the research question • Identify and refine sections that are too brief, too long, or unfocused • Evaluate supporting and supplementary materials 

Two rounds of Language Editing After scientific review, your manuscript undergoes two rounds of editing by native English-speaking experts. They refine clarity, reduce redundancy, and ensure technical accuracy, tone, and impact.  

Your scientific editor will review your manuscript from the perspective of a peer reviewer, providing a report based on: - Originality and significance assessment - Section-by-section analysis with suggestions for improvement - Recommendations for additional content and peer reviewer requirements - Journal compatibility check and additional requirements - Writing quality feedback and suggestions for substantive revisions  

This is an optional paid service exclusive to Top Impact Scientific Editing. Get expert feedback from a reviewer who has worked with top journals like Nature , NEJM , and The Lancet . Our expert evaluates your manuscript's quality, presentation, and research rigor, providing detailed recommendations to improve your chances of acceptance.

Our expert peer reviewers from top journals will:  • Critically evaluate your research paper • Provide further suggestions in the Top Impact Scientific Report • Enhance your paper's quality for impactful publication  

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Author shares the manuscript, references, and the target journal.

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Another two native English-speaking editors from your research field edit your paper to enhance flow and concision, and format it according to the requirements of your target journal.

We run an iThenticate plagiarism check on your manuscript and provide a report with actionable suggestions.

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Your editor writes a customized cover letter that highlights the significance of your research.

(Opaid option) Another peer reviewer with experience working with high Impact Factor journals such as Nature ,* NEJM ,* and The Lancet .* performs another review for content strength and research rigor.

What is the background of your Scientific Editors and Quality Assurance reviewers

Our Scientific Editors and Quality Assurance reviewers are working researchers with experiences in editing or reviewing for high Impact Factor journals. They are well-versed in the requirements of such journals and could best advise you from the point of view of journal editors and reviewers.

What is the difference between Enago’s Copyediting, Substantive Editing, and Top Impact Scientific Editing services?

We provide three editing services to suit different author expectations:

  • Copyediting – Manuscripts are put through a meticulous language check to correct all language, grammar, and punctuation errors. It is suitable for manuscripts that only require a final language editing.
  • Substantive Editing – On top of copyediting, this service improves the logical, structural, and presentation aspects of your manuscript. It is recommended for authors seeking to publish their research in SCI journals.
  • Top Impact Scientific Editing – This service is designed to meet the requirements of high IF journals. It features developmental editing by editors who have worked with journals such as Nature ,* NEJM ,* and The Lancet* ;a mock peer review, a plagiarism check, and an optional Quality Assurance Check.

Who performs the Language Review in Top Impact Scientific Editing?

The Language Review in the service flow of Top Impact Scientific Editing is performed by professional editors specializing in the same subject area of the research paper.  1. These editors are subject area experts with advanced degrees and extensive experience in research and scientific editing. 2. They specialize in specific fields of study, such as medicine, engineering, social sciences, etc., enabling them to understand the technical content and language used in academic papers.  3. They ensure that the papers adhere to academic standards, improve clarity and coherence, correct grammar and spelling errors, and also offer suggestions to strengthen arguments or refine the structure.  4. For academic editing services, we employ only editors with advanced degrees (PhD or Master's) and extensive experience in editing scholarly works to ensure high-quality outcomes

Can I submit a manuscript for Top Impact Scientific Editing regardless of which journal I wish to submit to?

Yes. Top Impact Scientific Editing provides the highest level of in-depth editing and can significantly improve your manuscript quality. This allows you to aim for publication in the best journal within your reach.

Do you guarantee successful acceptance of my manuscript to my target journal?

We cannot guarantee journal acceptance. Journal review is autonomous and is not subject to any third party influence and the decision largely depends on the merit of your research. However, we do guarantee that our Top Impact Scientific Editing expert editors will make every effort to strengthen your manuscript and give it the best chances of successful publication.

How long does the scientific editing process take?

Our Top Impact Scientific Editing service timeline varies based on the types of services and the length of the manuscript. Standard services typically take a few days, while more comprehensive editing may require additional time.  For an instant assessment of cost, please check out our editing pricing calculator. 

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Publishing your results is a vital step in the research lifecycle and in your career as a scientist. When you publish your results as a journal article, you make it possible for the scientific community to see it. Publishing your work allows you to get recognition for your results, and to exchange your ideas with the global scientific community. 

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If you feel that you would like some further support with writing your paper and understanding the peer review process, Springer Nature offer some services which may be of help.

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Article Contents

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Practical Steps to Writing a Scientific Manuscript

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Lars J Grimm, Jennifer A Harvey, Practical Steps to Writing a Scientific Manuscript, Journal of Breast Imaging , Volume 4, Issue 6, November/December 2022, Pages 640–648, https://doi.org/10.1093/jbi/wbac059

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Writing a scientific manuscript can be a very intimidating process for new writers. However, writing a scientific research article can be broken down into discrete steps to make the process more digestible. Radiology manuscripts have common conventions that differ from research in technical and other medical fields. The practical steps summarized within describe what to do before you start writing, successful writing strategies, and common writing styles. Templates for producing an abstract, introduction, methods, results, and discussion are outlined, along with tips to collect references and produce high quality figures. All writers can benefit from an outside writing perspective, and the practical steps described should ease the transition from a blank page to a finished manuscript.

There is no one “correct” way to write a scientific manuscript. However, using the order of methods, results, introduction, discussion, and abstract provides a straightforward approach to getting started.

Both the methods and results sections are relatively formulaic, but their contents depend upon the type of research study.

Tables and figures are often viewed more closely than the text and should highlight the major points of interest.

Writing a scientific manuscript can be an intimidating process if it is your first manuscript or if it has been a while since you last wrote a manuscript. Practice makes writing easier, but that is small consolation when you are staring at a blank screen with a steadily approaching deadline. Often, the biggest challenge is deciding how to begin, and this guide provides practical first steps for new writers. Experienced writers will invariably develop their own writing strategies, but everyone can learn from another’s perspective ( 1 ).

Writing a scientific manuscript is relatively formulaic, although every journal has a unique style. In 2005, Kliewer described a process for writing a scientific manuscript consisting of 18 paragraphs ( 1 ). There are many approaches to writing, and a formulaic approach is not meant to be the end-all to writing. However, the Kliewer article has an Altimetric score of 282, which is in the top 5% of all scientific articles, demonstrating the need for a framework for writing an original research article ( 1 ). We similarly provide practical steps to ease the transition from a blank page to a finished manuscript.

Before you start writing, it is helpful to confer with your research team to pick a target journal, divide up the writing tasks, and settle on a general timeline for submission. Who is included as an author and in what order is a complicated topic and should be decided early in the process ( 2 ). Ideally, a mentor or senior researcher would be included before study initiation to advise on the relevance and value of the proposed research. Additionally, all the data should already have been collected, analyzed, and ready for inclusion before you start writing. Picking a target journal will guide the organization of your manuscript, but choosing the right journal can be challenging. Journals are scored by their impact factor, which is an imperfect measure of the influence of their articles ( 3 ). In general, higher impact journals have lower acceptance rates, but it is more important to ensure your article fits within the scope of the journal. Radiology journals often focus on modality, clinical versus technical (eg, patient outcomes versus improving signal-to-noise ratios), organ system, or type of research. Skimming the table of contents of a recent issue can give a good sense of a journal, but it is often easiest to confer with a senior colleague. There are also online tools available to identify potential journals of interest ( 4 ). Once a journal is selected, it is important to carefully review the author guidelines as journals vary widely in their required formatting for length, content organization, reference formatting, and number of figures and tables, among other factors ( 5–9 ). Copying and pasting specific formatting requirements as notes into your manuscript ensures that you adhere to the guidelines and avoid wasted effort reformatting later. However, an advantage of submitting to the Journal of Breast Imaging is that formatting for journal style is not required at the first submission.

Although research is a collaborative endeavor, scientific manuscripts often suffer when the initial writing is split among too many authors. To avoid unexpected changes in tone and style, as well as overlaps in content and a lack of organization, it is often best to have one author write a rough first draft. This ensures continuity throughout the manuscript, and then, in subsequent drafts, contributing authors can provide recommended edits to their specific areas of expertise. If the manuscript is written by multiple individuals, it is important for one person to dedicate time to harmonizing the content before submission. Finally, although deadlines are helpful to ensure the project is completed in a timely fashion, it is best to incorporate flexibility. Good writing takes time, and an artificial, itemized deadline can add unnecessary pressure. However, if gaps between writing sessions grow too long, it can be hard to re-engage and remember where you left off. A timeline of three to four weeks is usually sufficient to complete a manuscript. However, for some authors it may be more comfortable to break the manuscript up into pieces and have shorter deadlines to facilitate discussions with coauthors throughout the process. Developing your own working style requires experimentation.

Successful writing strategies are uniquely personal, but there are common conventions that may aid early writers. Experiment with different environmental factors like music, caffeine, scenery, and time of day to discover what maximizes your productivity. It also takes time to get into the appropriate writing headspace, and there is a nonlinear relationship between good content and time, as productivity may be intermittent. Many writers will block out half days to be free of meetings and e-mail to allow uninterrupted time to focus. When writing, it is also easy to get bogged down researching specific references to support an argument, and you may lose your train of thought. It is often more efficient to leave placeholders for specific details (eg, “Seromas were present in X-Y% of mastectomy patients [refs].”) that can be filled in later. Getting a rough draft completed should be the primary goal, and then the manuscript can be iteratively revised among coauthors to produce a polished product for submission.

The traditional approach to writing is to proceed in a sequential fashion, beginning with the introduction and then continuing through the methods, results, discussion, and then the abstract. However, a manuscript can be written in any order. Starting with the methods is typically easy, since this information is probably already largely contained in your Institutional Review Board (IRB) application. Writing the results section flows from the methods. Consider what figures and tables will be needed to demonstrate the findings of the study. Then, transition to the more creative task of writing the introduction and discussion once grounded in the research outcomes. Jotting down notes for the introduction and discussion as you write the results can also remind you of important details you wish to cover. Finally, the abstract can be written once you have a comprehensive picture of the entire manuscript. Writers must also decide if they prefer to outline the manuscript first or start writing right away. Experimentation and practice can help to refine your most efficient writing strategy.

A manuscript should reflect your unique voice, but scientific writing has different conventions from other forms of writing. There are several excellent books and articles that provide a comprehensive overview of scientific writing ( 10–12 ). A common mistake is to write too many compound and complex sentences. It is often better to write short, digestible sentences that unambiguously convey a clear point. In general, the use of personal pronouns (eg, I, we, our) is discouraged as the style appears more casual. There are mixed opinions in the scientific literature about passive versus active voice, but in general the passive voice is overused and often the default choice in radiology literature ( 13 ). Active voice can make your writing more direct and easier to understand. Similarly, there is often confusion about which tense to use throughout the manuscript. A general rule of thumb is to use the present tense in the introduction and the discussion when describing other studies ( 14 ). The past tense is used in the methods, results, and discussion when reporting your study. There are exceptions to all these rules, and some journals will be explicit in their author guidelines, but a simple solution is to review a recent manuscript in your target journal.

The methods should be concise, while clearly articulating the steps to allow reproduction of the research. Reviewers focus heavily on the methods to ensure the study conclusions were appropriately developed. Overall, the methods are relatively formulaic, and the organization will depend heavily on the type of research performed. Subheadings are strongly encouraged to allow readers to jump to specific sections. The methods will often be organized in a semi-chronological order that begins with the study population, proceeds to describe the study activities, and finishes with the statistical analysis.

The first paragraph describes the study population and/or setting ( Table 1 ), with the first sentence describing the type of study and how it was managed by the IRB (eg, “This study received an exemption from the IRB”). A Health Insurance Portability and Accountability Act (HIPAA) statement is included for patient studies. State all inclusion and exclusion criteria clearly. At a minimum, these typically include sex/gender, age, and study dates. A figure with a flowchart showing how the final study population was created after the application of exclusion criteria is helpful ( Figure 1 ). A timeline of study activities may also be appropriate.

Structure of the Methods Section of a Scientific Manuscript With Brief Examples

ItemExamples
Type of study and IRB managementThis IRB-exempt HIPAA compliant retrospective study . . . . A waiver of consent was granted.
This prospective study was approved by our IRB and was compliant with the Health Insurance Portability and Accountability Act. Written informed consent was obtained from all study participants.
This survey study was IRB-exempt.
Define the study populationAll consecutive female patients aged 18-80 years old undergoing US-guided core-needle biopsy between January 2015 and December 2019 were included. Patients were excluded if they had a personal history of breast cancer, known bleeding disorder, or if follow-up of at least one year was not available.
For each patient, demographic information was collected including . . .
For each procedure, the needle gauge, number of samples,. . . were collected. The outcome of each procedure was collected and included incidence of hematoma formation, biopsy pathology results,. . .
All female patients aged 18-80 years old presenting for US-guided core-needle biopsy between January 2015 and August 2015 who met study criteria were invited to participate. Women were excluded if they were unable to provide informed consent, had a personal history of breast cancer, or a known bleeding disorder. Study patients were excluded from analysis if follow-up imaging of at least one year was not available.
Study details All US-guided biopsies were performed using one of two US machines (. . ., GE Healthcare, Chicago, IL or . . ., Siemens, Erlangen, Germany) using a 12-18 MHz transducer and a core-needle spring-loaded device (. . ., BARD,. . .). The number of samples obtained was at the discretion of the radiologist performing the procedure but generally ranged from 3 to 5 samples in our practice. The radiologists performing the procedures had 3 to 8 years of experience in breast imaging and US-guided breast biopsy.
Post-biopsy mammograms were used to assess the size of post-biopsy hematoma formation. If present, the hematoma was measured in three dimensions . . .
All US-guided biopsies were performed using one of two US machines (. . ., GE Healthcare, Chicago, IL or . . ., Siemens, Erlangen, Germany) using a 12-18 MHz transducer and a core-needle spring-loaded device (. . ., BARD,. . .). Five samples were obtained per study protocol. The radiologists performing the procedures had three to eight years of experience in breast imaging and US-guided breast biopsy.
Post-biopsy mammograms were obtained to assess the size of post-biopsy hematoma formation. If present, the hematoma was measured in three dimensions . . . . Visual assessment of bruising was performed by a nurse with eight years of experience in breast biopsy care and rated on a scale of 1 to 10 with 1 being none visible and 10 being gross bruising. For those patients with a hematoma identified, they were asked to return for a two-view (craniocaudal and mediolateral) mammogram in seven to 10 days as part of the study. Visual assessment of bruising was again performed by the same nurse.
Biopsy pathology results were obtained . . .
Five readers with three to ten years of experience reading breast MRI each reviewed cases independently using a clinical workstation. Readers were blinded to all clinical outcomes and no prior images were available for review. Readers were asked to report . . . using a 1 to 5 Likert scale with 1 representing most visible and 5 representing least visible.
A draft survey was developed and administered to a focus group of 5 radiologists who provided feedback. The final survey consisted of 12 questions ( ). The initial three questions were related to demographics and practice type. The remaining nine questions were related to the radiologists’ practices regarding antithrombic therapies and US-guided breast biopsy using a Likert scale.
The survey was administered to all practicing members of the Society of Breast Imaging; members-in-training, retired members, and those practicing outside of the U.S. were excluded. The survey was administered using Survey Monkey (city, state) and opened on November 5, 2021. The introductory invitation e-mail was sent on November 6, 2021 with two reminder emails sent at weekly intervals. The survey was closed on December 5, 2021.
Statistical analysisAggregate descriptive statistics were reported overall and for each subgroup. Comparisons between groups were made using a Pearson chi-square test. A -value of 0.05 was considered statistically significant and no corrections were made for multiple hypothesis testing. Statistical analysis was performed in Excel (Microsoft Corporation, Redmond, WA).
ItemExamples
Type of study and IRB managementThis IRB-exempt HIPAA compliant retrospective study . . . . A waiver of consent was granted.
This prospective study was approved by our IRB and was compliant with the Health Insurance Portability and Accountability Act. Written informed consent was obtained from all study participants.
This survey study was IRB-exempt.
Define the study populationAll consecutive female patients aged 18-80 years old undergoing US-guided core-needle biopsy between January 2015 and December 2019 were included. Patients were excluded if they had a personal history of breast cancer, known bleeding disorder, or if follow-up of at least one year was not available.
For each patient, demographic information was collected including . . .
For each procedure, the needle gauge, number of samples,. . . were collected. The outcome of each procedure was collected and included incidence of hematoma formation, biopsy pathology results,. . .
All female patients aged 18-80 years old presenting for US-guided core-needle biopsy between January 2015 and August 2015 who met study criteria were invited to participate. Women were excluded if they were unable to provide informed consent, had a personal history of breast cancer, or a known bleeding disorder. Study patients were excluded from analysis if follow-up imaging of at least one year was not available.
Study details All US-guided biopsies were performed using one of two US machines (. . ., GE Healthcare, Chicago, IL or . . ., Siemens, Erlangen, Germany) using a 12-18 MHz transducer and a core-needle spring-loaded device (. . ., BARD,. . .). The number of samples obtained was at the discretion of the radiologist performing the procedure but generally ranged from 3 to 5 samples in our practice. The radiologists performing the procedures had 3 to 8 years of experience in breast imaging and US-guided breast biopsy.
Post-biopsy mammograms were used to assess the size of post-biopsy hematoma formation. If present, the hematoma was measured in three dimensions . . .
All US-guided biopsies were performed using one of two US machines (. . ., GE Healthcare, Chicago, IL or . . ., Siemens, Erlangen, Germany) using a 12-18 MHz transducer and a core-needle spring-loaded device (. . ., BARD,. . .). Five samples were obtained per study protocol. The radiologists performing the procedures had three to eight years of experience in breast imaging and US-guided breast biopsy.
Post-biopsy mammograms were obtained to assess the size of post-biopsy hematoma formation. If present, the hematoma was measured in three dimensions . . . . Visual assessment of bruising was performed by a nurse with eight years of experience in breast biopsy care and rated on a scale of 1 to 10 with 1 being none visible and 10 being gross bruising. For those patients with a hematoma identified, they were asked to return for a two-view (craniocaudal and mediolateral) mammogram in seven to 10 days as part of the study. Visual assessment of bruising was again performed by the same nurse.
Biopsy pathology results were obtained . . .
Five readers with three to ten years of experience reading breast MRI each reviewed cases independently using a clinical workstation. Readers were blinded to all clinical outcomes and no prior images were available for review. Readers were asked to report . . . using a 1 to 5 Likert scale with 1 representing most visible and 5 representing least visible.
A draft survey was developed and administered to a focus group of 5 radiologists who provided feedback. The final survey consisted of 12 questions ( ). The initial three questions were related to demographics and practice type. The remaining nine questions were related to the radiologists’ practices regarding antithrombic therapies and US-guided breast biopsy using a Likert scale.
The survey was administered to all practicing members of the Society of Breast Imaging; members-in-training, retired members, and those practicing outside of the U.S. were excluded. The survey was administered using Survey Monkey (city, state) and opened on November 5, 2021. The introductory invitation e-mail was sent on November 6, 2021 with two reminder emails sent at weekly intervals. The survey was closed on December 5, 2021.
Statistical analysisAggregate descriptive statistics were reported overall and for each subgroup. Comparisons between groups were made using a Pearson chi-square test. A -value of 0.05 was considered statistically significant and no corrections were made for multiple hypothesis testing. Statistical analysis was performed in Excel (Microsoft Corporation, Redmond, WA).

Abbreviations: HIPAA, Health Insurance Portability and Accountability Act; IRB, Institutional Review Board.

Example diagram that demonstrates how the study population was defined.

Example diagram that demonstrates how the study population was defined.

The subsequent paragraphs depend on the study design. Essentially, explain what was done with the study population and how it was done.

Retrospective Study

For retrospective studies, it is important to define the standards of practice for the study population under investigation. The imaging equipment, including vendor information (manufacturer, city of headquarters, state), should be specified. For routine procedures or clinical tasks (eg, stereotactic breast biopsy), explicit details do not need to be described unless they are germane to the study or varied between study locations. Provide the experience of the radiologists performing the interpretations or procedures during the study period.

Reader Study

For reader studies, it is important to describe how the images/cases were selected and the conditions under which the radiologists reviewed the images (eg, research workstation). Accompanying figures and/or tables may be helpful to describe the research conditions. Specify any training, education, or guidance provided to the readers. Describe all metrics reported by the readers.

Survey Study

A manuscript reporting the results of a survey will have a section on how the survey was developed, tested, and administered. The full text of the survey should be made available in the manuscript or as an appendix.

The last paragraph of the methods is reserved for the analysis plan, including the statistics. A description of how data were coded and analyzed, which statistical tests were used, and which statistical software was used should be described. For complicated statistical analyses, the statistician should write this section to ensure accuracy. Journals increasingly include a statistical reviewer, so it is important to be clear about the analysis plan. It is also typical to define the threshold for statistical significance (eg, P- value ≤ 0.05) along with any efforts to control for multiple hypothesis testing.

The results should also be laid out in a straightforward manner with regular use of subheadings ( Table 2 ). The length of the results section does not reflect the amount of work involved in a research project, so avoid filler content. A simple five-minute survey might have a dozen questions to report, while a complicated deep learning algorithm might yield a single model performance metric. Provide all pertinent positive, negative, and non-significant findings in the text or tables to provide a comprehensive picture of the study.

Structure of the Results Section of a Scientific Manuscript With Typical Examples

ItemExamples
Define the study population During the study period, 532 women underwent US-guided breast core-needle biopsy. Of these, 35 were excluded due to personal history of breast cancer and 6 were excluded due to known bleeding disorder. Of the remaining 491 patients, 63 were excluded as follow-up of at least one year was not available. The remaining 428 patients make up the study group.
The mean patient age was 54.3 years (range 24-82 years). The patients were predominantly White (389/428, 90.9%) and post-menopausal (365/428, 85.3%) ( ).
During the study period, 124 women underwent US-guided core-needle biopsy. Of these, 62 agreed to participate in the study and gave informed study consent.
The mean patient age was 54.3 years (range 24-82 years). The patients were predominantly White (47/62, 75.8%) and post-menopausal (52/62, 83.9%) ( ).
Information regarding the readers may be provided here but is typically included in the methods.
During the survey period, 345 Society of Breast Imaging members completed the survey for a response rate of 22.5% (345/1534). Of these, 47 were excluded because of being a member-in training, retired, or practicing outside of the U.S. The remaining 298 respondents make up the study group.
The mean respondent age was 54.3 years (range 34-72 years). Respondents were most commonly in practice for 10 to 14 years (156/298, 52.3%) and were in academic practice (170/298, 57.0%) ( ). Geographic distribution of respondents was relatively balanced with the most common location being the Northeast (89/298, 29.9%).
Study results The majority of women had no hematoma demonstrated on the post-biopsy mammogram (44/62, 71.0%) (Table 3). The vast majority of those with a hematoma on the post-biopsy mammogram had a small hematoma measuring less than 1 cm  (10/18, 55.6%). The mean hematoma size was 1.4 cm (range . . . ). The mean visual assessment of bruising after the procedure was . . . with the mode being 1 (range).
The majority of women had no hematoma demonstrated on the post-biopsy mammogram (44/62, 71.0%) (Table 3). The vast majority of those with a hematoma demonstrated on the post-biopsy mammogram, and most were small, measuring less than 1 cm (10/18, 55.6%). The mean hematoma size was 1.4 cm (range . . .). The mean visual assessment of bruising after the procedure was . . . with the mode being 1 (range).
All 18 patients with post-biopsy hematoma returned between seven and 10 days for reassessment, with the mean follow-up of 8.3 days. Only 3 of the 18 patients (16.7%) had a residual hematoma on repeat mammogram. The mean size was . . ., which was significantly decreased compared to the post-biopsy mammogram (  = 0.035). Visual assessment . . .
Biopsy pathology results showed 15 malignant results (15/62, 24.2%) (Table 4), with the most common result being invasive ductal carcinoma (9/15, 60.0%). Malignant pathology outcome was statistically significantly associated with the presence of post-biopsy hematoma (12/18, 66.7%) (  = 0.004) as well as the size of hematoma (mean . . ., range . . .) (  = 0.034). Visual assessment . . . . At follow-up,. . .
The mean area under the receiver operating characteristic curve of reader performance to predict malignancy was 0.74 (range 0.43-0.92,  = 0.023) when reporting a percentage likelihood of malignancy. The mean reader confidence was 57% (range 34%-75%). The interobserver variability of the readers was fair (kappa = 0.31) for the use of BI-RADS final assessment categories.
Most respondents indicated that they never cancel procedures for patients who are taking antithrombotic medications (200/345, 60.0%). This rate was significantly higher for respondents in academic practices (75/100, 75%) than for those in private practice (100/200, 50.0%) or who did not provide information on practice type (25/45, 55.6%) (  = 0.035).
ItemExamples
Define the study population During the study period, 532 women underwent US-guided breast core-needle biopsy. Of these, 35 were excluded due to personal history of breast cancer and 6 were excluded due to known bleeding disorder. Of the remaining 491 patients, 63 were excluded as follow-up of at least one year was not available. The remaining 428 patients make up the study group.
The mean patient age was 54.3 years (range 24-82 years). The patients were predominantly White (389/428, 90.9%) and post-menopausal (365/428, 85.3%) ( ).
During the study period, 124 women underwent US-guided core-needle biopsy. Of these, 62 agreed to participate in the study and gave informed study consent.
The mean patient age was 54.3 years (range 24-82 years). The patients were predominantly White (47/62, 75.8%) and post-menopausal (52/62, 83.9%) ( ).
Information regarding the readers may be provided here but is typically included in the methods.
During the survey period, 345 Society of Breast Imaging members completed the survey for a response rate of 22.5% (345/1534). Of these, 47 were excluded because of being a member-in training, retired, or practicing outside of the U.S. The remaining 298 respondents make up the study group.
The mean respondent age was 54.3 years (range 34-72 years). Respondents were most commonly in practice for 10 to 14 years (156/298, 52.3%) and were in academic practice (170/298, 57.0%) ( ). Geographic distribution of respondents was relatively balanced with the most common location being the Northeast (89/298, 29.9%).
Study results The majority of women had no hematoma demonstrated on the post-biopsy mammogram (44/62, 71.0%) (Table 3). The vast majority of those with a hematoma on the post-biopsy mammogram had a small hematoma measuring less than 1 cm  (10/18, 55.6%). The mean hematoma size was 1.4 cm (range . . . ). The mean visual assessment of bruising after the procedure was . . . with the mode being 1 (range).
The majority of women had no hematoma demonstrated on the post-biopsy mammogram (44/62, 71.0%) (Table 3). The vast majority of those with a hematoma demonstrated on the post-biopsy mammogram, and most were small, measuring less than 1 cm (10/18, 55.6%). The mean hematoma size was 1.4 cm (range . . .). The mean visual assessment of bruising after the procedure was . . . with the mode being 1 (range).
All 18 patients with post-biopsy hematoma returned between seven and 10 days for reassessment, with the mean follow-up of 8.3 days. Only 3 of the 18 patients (16.7%) had a residual hematoma on repeat mammogram. The mean size was . . ., which was significantly decreased compared to the post-biopsy mammogram (  = 0.035). Visual assessment . . .
Biopsy pathology results showed 15 malignant results (15/62, 24.2%) (Table 4), with the most common result being invasive ductal carcinoma (9/15, 60.0%). Malignant pathology outcome was statistically significantly associated with the presence of post-biopsy hematoma (12/18, 66.7%) (  = 0.004) as well as the size of hematoma (mean . . ., range . . .) (  = 0.034). Visual assessment . . . . At follow-up,. . .
The mean area under the receiver operating characteristic curve of reader performance to predict malignancy was 0.74 (range 0.43-0.92,  = 0.023) when reporting a percentage likelihood of malignancy. The mean reader confidence was 57% (range 34%-75%). The interobserver variability of the readers was fair (kappa = 0.31) for the use of BI-RADS final assessment categories.
Most respondents indicated that they never cancel procedures for patients who are taking antithrombotic medications (200/345, 60.0%). This rate was significantly higher for respondents in academic practices (75/100, 75%) than for those in private practice (100/200, 50.0%) or who did not provide information on practice type (25/45, 55.6%) (  = 0.035).

Typically, the first paragraph of the results will present a summary of the study population along with a table that provides detailed demographic information. Provide a narrative summary of the important findings and avoid repeating information accessible to the reader from the tables. For example, “The majority of women were White (28/50, 56%) and post-menopausal (31/50, 62%) with at least two prior mammograms for comparison (35/50, 70%) as shown in Table 1 .”

The subsequent paragraphs follow the flow of the methods section, presenting the findings along with any relevant statistical metrics (ie, P -values). Exact P -values provide more context compared with a less than number (eg, P  = 0.023 is preferred over P  < 0.05). Of note, the term “significant” implies statistical significance in scientific writing, and relevant statistical information ( P -value, odds ratio, etc) should be provided.

Figures and tables are very helpful, especially for complicated analyses with large numbers of variables. Secondary data that were collected but not important to the primary findings can be placed in supplemental tables. Narrative summary information is again helpful to capture the major points, with references to the tables and/or figures for specific details. It is typical to report both percentages and numbers as appropriate (eg, 30% [3/10]) so that readers understand the context of any metrics. Be consistent in the number of significant digits and choose a threshold that has real-world meaning (eg, the mean lymph node size is 3.4 cm and not 3.428 cm). Present results in a neutral tone without any references to prior literature or descriptions of the implications of the findings.

Now that you have developed the important points of your study findings, focus on the introduction and discussion. The introduction is the space to provide background information to justify why your research was done. Different fields have widely divergent conventions about the organization and length of the introduction, but clinical radiology journals err on the side of shorter and more concise introductions (~300-500 words). New authors often confuse content between the introduction and the discussion. A simple convention is to think of the introduction as the clinical/research world before your study was performed. Your study was needed to fill in the gaps in knowledge that previously existed. There is no need to provide information that the journal audience will already be familiar with. For Journal of Breast Imaging readers, for example, it is not necessary to provide basic breast cancer statistics. The discussion then places your findings in the context of the new clinical/research world and describes future directions.

There are many ways to structure the introduction, but a simple template is two short background paragraphs concluded by a very brief paragraph describing the purpose of the study. Imagine a funnel that starts very broadly to discuss the research environment and tapers to this specific study. Most studies can be broken down into the intersection of two topics of interest, which provides a simple narrative for the reader. Imagine you were writing a manuscript on alcohol ablation for postoperative seromas. The first paragraph would focus on postoperative seromas—incidence, biology, treatment options, etc. The second paragraph would focus on alcohol ablation—mechanism of action, successful non-breast clinical scenarios, paucity of data on breast seroma alcohol ablations, etc. The final paragraph would then explain in two to three sentences why your study was done based on the intersection of the preceding two paragraphs. An explicit statement defining your hypothesis or purpose is recommended and required by most journals. The stated purpose of the study at the conclusion of the introduction mirrors the objective statement of the abstract.

The discussion is where you summarize the important findings of your study, explain the significance of the findings, and describe how they compare and contrast to the published literature to date. While your findings may be groundbreaking, superlatives like “first” or “best” should be avoided. It is also important to never report new findings in the discussion that were not in the results. However, discussing next steps or future directions for research or clinical applications is encouraged to place your findings in the context of the larger body of current and future studies.

Typically, the first paragraph of the discussion summarizes the major finding(s) of the study. The subsequent one to two paragraphs will then highlight additional pertinent positive or negative findings. The following one to two paragraphs describe why the results are important and place them in the context of other studies. A simple convention is to summarize your research finding in one to two sentences and then describe how the finding relates to prior published work. Qualifiers are helpful (eg, “It was surprising . . .” or “Our results confirm previous work . . .”) to place your findings in context with prior work and your initial hypothesis. Providing specific data from prior studies is more helpful than generalization (eg, “Collin et al (reference number) identified post-biopsy hematomas in only 2% (2/100) of patients undergoing US-guided core-needle biopsy in contrast to our study identifying 7% (7/100) of patients. However, our study used post-biopsy mammograms, while the prior study . . .”). Gaps in knowledge or proposed next steps are included when appropriate.

A limitations paragraph is usually the second to last paragraph of the discussion. All studies have limitations, and it is important to describe the major ones, posit their impact on the results, and list any amelioration steps. For example, “Our study population had a lower proportion of Hispanic women than the general population, despite our outreach efforts. This limited our ability to perform subgroup analysis.” While it is important to describe the major limitations to contextualize the findings, it is not necessary to list every conceivable limitation. Reviewers will invariably request that additional limitations be included, and if the list of limitations is too long, it may inappropriately undermine the manuscript.

The last paragraph of the discussion is the conclusion and includes a high-level narrative summary of the findings. Caution is suggested when making conclusions about the findings of the study to ensure that they are not overstated. The results must support the conclusion. This may be the only part of the discussion that a casual reader actually reads, so summarize the major take-home messages. It is often appropriate to include one or two sentences about next steps (eg, “These results justify further work in a multi-institution prospective setting”). This is your parting message to the reader, and there is some flexibility to include an aspirational tone to your final message.

Although the abstract is the shortest piece of a manuscript, it is often the only piece most readers will see. Abstracts are visible on search engines like PubMed or Google Scholar even if a reader does not access the full text ( 15 , 16 ). There are usually minor formatting differences between journals, but it is most important to note the total word count, usually 250 words as search engines typically truncate the abstract at this number. Summarizing a manuscript of 2000 to 3000 words into 250 words is a logistical challenge that may involve creative use of hyphenations, parallel structure, abbreviations, and brief language. It is impossible to describe all the details of the methods and results as well as the nuances of the introduction and discussion. Instead, summarize the major findings and emphasize the key take-home messages. The abstract is the opportunity to sell a prospective reader on why they should read the entire manuscript.

In the Journal of Breast Imaging , the abstract headings are objective, methods, results, and conclusion. The objective is typically no more than one or two sentences and mirrors the purpose statement that is the last sentence of the introduction. The methods typically opens with the type of study and IRB information (eg, “This retrospective study was IRB-exempt”). The next sentence or two describe the study design and may include how the study population was identified, followed by what was done. The methods section closes with a sentence on statistical analysis. The results section typically opens with the defined study population and then a summary of the important results. The methods and results sections should have the most words of your abstract. The conclusion is typically one or two sentences summarizing the important results and future directions. As in the discussion, care must be made to not overstate your conclusions.

A scientific manuscript should have ample supporting references to justify the research and contextualize the findings. Identifying appropriate references can be overwhelming, but a short primer on PubMed or Google Scholar with a librarian can teach you successful search strategies ( 15 , 16 ). For narrow projects, it may be appropriate to cite the entire body of published work. For projects with larger areas of interest (eg, breast cancer screening), there may be thousands of references. A practical strategy is to review a recent review article or similar scientific manuscript to find potential references. Looking at articles that subsequently cite an article may lead to important current articles expanding on the original findings. Search engines can also be sorted by citation counts, which facilitates identification of the most cited articles. In general, it is better to cite more recent articles and those from well-known journals to ensure that the references are current and well vetted. It is also best to reference a primary scientific manuscript rather than a review article.

Reference managers such as EndNote (Clarivate, Philadelphia, PA), RefWorks (ProQuest, Ann Arbor, MI), or Mendeley Desktop (Elsevier, Amsterdam, Netherlands) can synchronize the order of references within the manuscript and are a valuable time-saving tool. They allow text to be moved within the manuscript while ensuring appropriate linkage and ordering of references. Reference managers also facilitate easy switching of formats between journal requirements. Formatting references in the style of the journal can be performed by reviewing the journal’s “Instructions to Authors” and often downloading the appropriate format into the reference manager. The Journal of Breast Imaging follows the 11 th edition of the American Medical Association (AMA) Manual of Style ( 17 ). Finally, although journals have maximum but not minimum citation limits, including less than 15 to 20 references raises concerns that adequate background research was not performed.

Collecting compelling clinical images to support the manuscript narrative is critically important for a radiology manuscript. Review the author guidelines for requirements on the number of figures, image resolution, and file formats (eg, JPEG, GIF, TIFF). Use annotations, such as arrows or circles, liberally to highlight major findings. The small figure sizes require careful cropping, windowing, and leveling of clinical images. Journals will specify the minimum number of dots per inch (dpi). It is not uncommon to save low resolution images initially and realize later that the images are an insufficient dpi and must be redone. Saving a raw high-resolution master copy in reserve is helpful. An easy trick to acquiring high-resolution clinical images is to zoom in at the clinical workstation and then use a screen grab tool to capture an overly large but correctly framed image. That large image can then be shrunk down to the appropriate dimensions while keeping the dpi very high. Also, check to make sure your software program is not downgrading the image sizes by default. Some journals, including the Journal of Breast Imaging , prefer consolidation of all image parts for each figure with submission of one image file. All of these tasks are easily performed in commonly available software programs such as PowerPoint, Paint, or Paint 3D (Microsoft Corporation, Redmond, WA). The edited images can then be saved in the appropriate format per the author guidelines ( 5–9 ).

Similarly, each journal has a particular style for figure legends. Many journals, including the Journal of Breast Imaging , prefer a narrative approach rather than listing each image with its description (eg, “On transverse ( A ) and sagittal ( B ) US images, an oval circumscribed mass (arrows) . . . . No internal vascularity was seen on color Doppler imaging ( C )”). Abbreviations are included at the end of the figure legend. Reviewing the author guidelines and recent journal articles is helpful.

Tables should present the study data in a succinct fashion. They provide a more comprehensive display of the data beyond the highlights presented in the text. In a research article, the first table typically provides the demographic information of the study population. For studies comparing two groups, demographic information might be listed overall and for each group to allow for easy comparison. Subsequent tables provide relevant data from the results along with statistical information. It may take some trial and error to optimize the layout of a large table, but it is worth the effort as readers often focus on the results from the table. Tables usually have short, succinct titles, unlike the more narrative figure legends. Additional comments or qualifiers are added as a footnote to the table, often with a symbol (eg, *, ǂ) denoting what section of the table they are referencing. Readers should be able to interpret the table without reading the text, and thus, any abbreviations should be included at the bottom of the table.

Other Items

The title should inform the reader of the basic research question. A good title is not too long or too short and captures the reader’s attention. A pithy approach may be acceptable, but it is best to review prior journal publication titles to ensure this approach is suitable. For example, the title may be a question (eg, “Is synthetic mammography adequate to detect amorphous calcifications?”) or may be the conclusion of the study (eg, “Synthetic mammography adequately detects amorphous calcifications”).

Journals usually require three to five keywords that facilitate indexing and search engine identification. A thoughtful approach that errs on the side of being more general is likely to increase visibility.

Many journals also ask for some additional journal specific items. In the Journal of Breast Imaging , the key messages provide two to four summary statements of the research. In essence, provide several points that you would like the reader to take away after reading the article. Condensing your major points into very short key messages can be challenging, but the content is highly viewed and thus valuable.

Journals manage abbreviations in different ways. Generally, abbreviations are expanded at first use in the abstract, body of the manuscript, each figure legend, and each table title. An abbreviation is expanded if used at the beginning of a sentence. Some abbreviations do not need to be expanded at first use per the AMA style guide ( 17 ). Common abbreviations in imaging that do not need to be expanded include DNA, RNA, UV (ultraviolet), CI (confidence interval), SD (standard deviation), SE (standard error), and SEM (standard error of the mean). In the Journal of Breast Imaging , some additional abbreviation never need expansion, including MRI, US, PET, PET-CT, and CT. In the abstract, IRB and BI-RADS can be used without expansion but are expanded at first use in the main text. In figure legends or tables, BI-RADS can be used without expansion. Note that in the Journal of Breast Imaging , US is used for ultrasound while U.S. is used for the United States. Nonstandard abbreviations are generally avoided in the title or headings, but standard abbreviations such as MRI or BI-RADS are fine. The use of many nonconventional abbreviations can confuse and slow down the reader.

Submitting the Manuscript

Review the author guidelines for the journal that you have chosen one more time. Most imaging journals require a blinded manuscript, separate title pages, and individual files for images at first submission. The title page will often require detailed author information and disclosures. Where author initials are included, use “X.X.X.” and a similar format for institutions in the manuscript. Many journals, including the Journal of Breast Imaging , do not require journal specific formatting at the initial submission, but it is required for subsequent resubmission if the article moves forward.

Acceptance of a scientific manuscript at initial submission is extremely rare. Most articles that are subsequently published will move from major revision to minor revision to acceptance. Note that a decision of “reject– resubmission allowed” often means that major reanalysis or rewriting of the manuscript is needed. These papers will often undergo a new set of reviews at resubmission. Many of these manuscripts will move on to publication if concerns are adequately addressed. Articles that are rejected without further consideration can often be revised based on reviewer comments and submitted to a different journal.

While reviewer comments may feel hurtful, they are meant to improve the paper and are not personal. Articles often move from just okay to excellent during the review process.

Journal editors and staff are typically happy to help you with problems or questions.

Every scientific manuscript creates a unique set of challenges for the writer, but the practical steps described here should provide a solid conceptual framework. Getting started is often the hardest part of writing, and the goal is to create a draft, no matter how rough. By breaking the manuscript down into discrete sections, you can more easily make progress. Last, a writing mentor is an invaluable resource. Beginning and experienced writers alike can always benefit from some outside perspective. Good luck and happy writing!

None declared.

J.A.H. is Editor-in-Chief of the Journal of Breast Imaging . As such, she was excluded from the review process. L.J.G. declares no conflict of interest.

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The Biosemantics Group. Journal/author name estimator . Available at: https://jane.biosemantics.org . Accessed July 8, 2022 .

Journal of Breast Imaging. Instructions for authors . Available at: https://academic.oup.com/jbi/pages/General_Instructions . Accessed March 14, 2022 .

Radiological Society of North America. Radiology publication instructions for authors . Available at: https://pubs.rsna.org/page/radiology/author-instructions . Accessed March 14, 2022 .

American Roentgen Ray Society. Guidelines for authors . Available at: https://www.arrs.org/AJR/AuthorGuidelines . Accessed March 14, 2022 .

Academic Radiology. Guide for authors . Available from: https://www.elsevier.com/journals/academic-radiology/1076-6332/guide-for-authors . Accessed March 14, 2022 .

Journal of the American College of Radiology. Guide for authors . Available at: https://www.elsevier.com/journals/journal-of-the-american-college-of-radiology/1546-1440/guide-for-authors . Accessed March 10, 2022 .

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Gunderman RB , Steinmeyer LA. The passive voice . Acad Radiol 2015 ; 22 ( 9 ): 1206 – 1207 .

Kotsis SV , Chung KC. A guide for writing in the scientific forum . Plast Reconstr Surg 2010 ; 126 ( 5 ): 1763 – 1771 .

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Christiansen S , Iverson C , Flanagin A. AMA Manual of Style: A Guide for Authors and Editors . Oxford University Press ; 2020 .

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