research question about health care

300+ Health Related Research Topics For Medical Students(2023)

In the world of academia and healthcare, finding the right health-related research topics is essential. Whether you are a medical student, a college student, or a seasoned researcher, the choice of your research topic greatly impacts the quality and relevance of your work. This blog, health related research topics, is your guide to selecting the perfect subject for your research.

In this post, we will share 5 invaluable tips to help you pick suitable health-related research topics. Additionally, we will outline the crucial elements that every health-related research paper should incorporate.

Furthermore, we’ve compiled a comprehensive list of 300+ health-related research topics for medical students in 2023. These include categories like mental health, public health, nutrition, chronic diseases, healthcare policy, and more. We also offer guidance on selecting the right topic to ensure your research is engaging and meaningful.

So, whether you are delving into mental health, investigating environmental factors, or exploring global health concerns, health-related research topics will assist you in making informed and impactful choices for your research journey, even within the hardest medical specialties .

What Is Health Research?

Table of Contents

Health research is like detective work to understand how our bodies work and how to keep them healthy. It’s like asking questions and finding answers about things like sickness, medicine, and how to live better. Scientists and doctors do health research to learn new ways to treat illnesses, like finding better medicines or discovering new ways to prevent diseases.

Health research is a puzzle, where scientists collect information, do experiments, and study many people to find out what makes us healthy or sick. They want to find clues and put them together to help us stay well and live longer. So, health research is like a quest to learn more about our bodies and find ways to make them work their best, keeping us happy and strong.

5 Useful Tips For Choosing Health Related Research Topics

Here are some useful tips for choosing health related research topics: 

Tip 1: Follow Your Interests

When picking a health research topic, it’s a good idea to choose something you’re curious and excited about. If you’re interested in a subject, you’ll enjoy learning more about it, and you’ll be motivated to do your best. So, think about what aspects of health catch your attention and explore those areas for your research.

Tip 2: Consider Relevance

Your research topic should be meaningful and have real-world importance. Think about how your research can contribute to solving health problems or improving people’s well-being. Topics that are relevant and can make a positive impact on health and healthcare are usually more valuable.

Tip 3: Check Available Resources

Before deciding on a research topic, make sure you have access to the necessary resources, like books, articles, or equipment. It’s important that you can find the information and tools you need to conduct your research effectively.

Tip 4: Keep It Manageable

Select a research topic that you can handle within the available time and resources. It’s better to choose a more focused and manageable topic rather than something too broad or complex. This way, you can delve deep into the subject and produce meaningful results.

Tip 5: Seek Guidance

Don’t hesitate to ask for guidance from teachers, professors, or experts in the field. They can help you refine your research topic, provide valuable insights, and suggest improvements. Seeking advice can make your research journey smoother and more successful.

Important Elements That Must Be Present In A Health Related Research Paper

Here are some important elements that must be present in a health related research paper: 

1. Clear Title and Introduction

A good health research paper needs a clear title that tells people what it’s about. The introduction should explain why the research is important and what the paper will discuss. It’s like the map that shows the way.

2. Methods and Data

You should describe how you did your research and the data you collected. This helps others understand how you found your information. It’s like showing your work in math so that others can check it.

3. Results and Conclusions

After doing your research, you need to show what you discovered. Share the results and what they mean. Conclusions tell people what you found out and why it’s important. It’s like the “So what?” part of your paper.

4. Citations and References

When you use other people’s ideas or words, you need to give them credit. Citations and references show where you got your information. It’s like saying, “I learned this from here.”

5. Clear Language and Organization

Make sure your paper is easy to read and well-organized. Use clear and simple language so that everyone can understand. Organize your paper logically, with a beginning, middle, and end, like a good story. This makes your research paper more effective and useful.

In this section, we will discuss 300+ health related research topics for medical students(2023): 

Health Related Research Topics

• How living choices affect health and how long people live.
• Ways to make it easier for people in underserved areas to get medical care.
• The role of DNA in determining susceptibility to different diseases.
• There are differences in health between race and ethnic groups and between socioeconomic groups.
• Checking how well health education programs encourage people to behave in a healthy way.
• The effects that stress has on the body and mind.
• Looking at the pros and cons of different vaccine plans.
• The link between how well you sleep and your general health.
• The use of technology to make health care better.
• How cultural beliefs and habits affect how people seek health care.

Mental Health Related Research Topics

• Identifying the factors contributing to the rise in mental health disorders among adolescents.
• Examining the effectiveness of different therapeutic approaches for treating depression and anxiety.
• How social media can hurt your mental health and self-esteem.
• We are looking into the link between traumatic events in youth and mental health problems later in life.
•  Stigma and racism in mental health care, and how they make people less healthy.
•  Ways to lower the suicide rate among people who are at high risk.
•  Exercise and other forms of physical action can help your mental health.
•  The link between using drugs and having mental health problems.
•  Mental health support for frontline healthcare workers during and after the COVID-19 pandemic.
•  Exploring the potential of digital mental health interventions and apps.

Health Related Research Topics For College Students

• The impact of college stress on physical and mental health.
•  Assessing the effectiveness of college mental health services.
•  The role of peer influence on college students’ health behaviors.
•  Nutrition and dietary habits among college students.
•  Substance use and abuse on college campuses.
•  Investigating the prevalence of sleep disorders among college students.
•  Exploring sexual health awareness and behaviors among college students.
•  Evaluating the relationship between academic performance and overall health.
•  The influence of social media on college students’ health perceptions and behaviors.
•  Ideas for getting people on college grounds to be more active and eat better.

Public Health Related Research Topics

• Evaluating the impact of public health campaigns on smoking cessation .
•  The effectiveness of vaccination mandates in preventing disease outbreaks.
•  Looking into the link between the health of the people in cities and the quality of the air.
•  Strategies for addressing the opioid epidemic through public health initiatives.
•  The role of public health surveillance in early disease detection and response.
•  Assessing the impact of food labeling on consumer choices and nutrition.
•  Looking at how well public health measures work to lower the number of overweight and obese kids.
•  The importance of water quality in maintaining public health.
•  This paper examines various strategies aimed at enhancing mother and child health outcomes in emerging nations.
•  Addressing the mental health crisis through public health interventions.

Mental Disorder Research Topics

• The mental health effects of social isolation, with a particular focus on the COVID-19 pandemic.
•  Exploring the relationship between mental health and creative expression.
•  Cultural differences influence the way in which mental health disorders are perceived and treated.
•  The use of mindfulness and meditation techniques in managing mental health.
•  Investigating the mental health challenges faced by LGBTQ+ individuals.
•  Examining the role of nutrition and dietary habits in mood disorders.
•  The influence of childhood experiences on adult mental health.
•  Innovative approaches to reducing the stigma surrounding mental health.
•  Mental health support for veterans and active-duty military personnel.
•  The relation between sleep disorders and mental health.

Nutrition and Diet-Related Research Topics

• The impact of dietary patterns (e.g., Mediterranean, ketogenic) on health outcomes.
•  Investigating the role of gut microbiota in digestion and overall health.
•  The effects of food labeling and nutritional education on dietary choices.
•  The correlation between chronic disease prevention and nutrition.
•  Assessing the nutritional needs of different age groups (children, adults, elderly).
•  Exploring the benefits and drawbacks of various diet fads (e.g., intermittent fasting, veganism).
•  The role of nutrition in managing obesity and weight-related health issues.
•  Studying nutrition and mental wellness.
•   Impact of food insecure areas on population health and diet.
•  Strategies for promoting healthy eating in schools and workplaces.

Chronic Disease Research Topics

• The contribution of inflammation to the progression and development of chronic diseases.
•  Evaluating the effectiveness of lifestyle modifications in managing chronic conditions.
•  The impact of chronic stress on various health conditions.
•  Investigating disparities in the management and treatment of chronic diseases among different populations.
•  Exploring the genetics of chronic diseases and potential gene therapies.
•  The impact that environmental factors, including pollution, have on the prevalence of chronic diseases.
•  Assessing the long-term health consequences of childhood obesity.
•  Strategies for improving the quality of life for individuals living with chronic diseases.
•  The importance of maintaining a healthy level of physical activity and exercise for both the prevention and treatment of chronic illnesses.
•  Investigating innovative treatments and therapies for chronic diseases, such as gene editing and personalized medicine.

Healthcare Policy and Access Research Topics

• Assessing how the Affordable Care Act affects healthcare access and outcomes.
•  Telehealth’s impact on rural healthcare access.
•  Investigating the cost-effectiveness of various healthcare payment models (e.g., single-payer, private insurance).
•  Assessing healthcare disparities among different racial and socioeconomic groups.
•  The influence of political ideologies on healthcare policy and access.
•  Healthcare professional shortage solutions, including nurses and doctors.
•  The impact of malpractice reform on healthcare quality and access.
•  Examining the role of pharmaceutical pricing and regulation in healthcare access.
•  The use of technology in streamlining healthcare administration and improving access.
•  Exploring the intersection of healthcare policy, ethics, and patient rights.

Environmental Health Research Topics

• The impact of climate change on public health, including increased heat-related illnesses and vector-borne diseases.
•  Studying air pollution’s effects on the cardiovascular and respiratory systems.
•  Assessing the health consequences of exposure to environmental toxins and pollutants.
•  Exploring the role of green spaces and urban planning in promoting public health.
•  The impact of water quality and sanitation on community health.
•  Strategies for minimizing the health risks linked with natural catastrophes and extreme weather events.
•  Investigating the health implications of food and water security in vulnerable populations.
•  The influence of environmental justice on health disparities.
•  Evaluating the benefits of renewable energy sources in reducing air pollution and promoting health.
•  The role of public policy in addressing environmental health concerns.

Infectious Disease Research Topics

• Tracking the evolution and spread of infectious diseases, including COVID-19.
•  Investigating the effectiveness of vaccination campaigns in preventing outbreaks.
•  Antimicrobial resistance and strategies to combat it.
•  Assessing the role of vector-borne diseases in global health, such as malaria and Zika virus.
•  The impact of travel and globalization on the spread of infectious diseases.
•  Strategies for early detection and containment of emerging infectious diseases.
•  The role of hygiene and sanitation in reducing infectious disease transmission.
•  Investigating the cultural factors that influence infectious disease prevention and treatment.
•  The use of technology in disease surveillance and response.
• Examining the ethical and legal considerations in managing infectious disease outbreaks.

Women’s Health Research Topics

• Exploring the gender-specific health issues faced by women, such as reproductive health and menopause.
• Investigating the impact of hormonal contraception on women’s health.
• Assessing the barriers to accessing quality maternal healthcare in low-income countries.
• The role of gender-based violence in women’s mental and physical health.
• Strategies for promoting women’s sexual health and reproductive rights.
• Exploring the relationship between breast cancer and genetics.
• The influence of body image and societal pressures on women’s mental health.
• Investigating healthcare disparities among different groups of women, including racial and ethnic disparities.
• Strategies for improving access to women’s healthcare services, including family planning and prenatal care.
• The use of telemedicine and technology to address women’s health needs, especially in remote areas.

Children’s Health Research Topics

• The impact of early childhood nutrition on long-term health and development.
• Environmental toxin exposure and child health.
• Assessing the role of parenting styles in children’s mental and emotional well-being.
• Strategies for preventing and managing childhood obesity.
• The influence of media and technology on children’s physical and mental health.
• Exploring the challenges faced by children with chronic illnesses and disabilities.
• The relevance of early child mental wellness and developmental condition intervention.
• Investigating the role of schools in promoting children’s health and well-being.
• Strategies for addressing child healthcare disparities, including access to vaccines and preventive care.
• Adverse childhood experiences and adult health.

Aging and Gerontology Research Topics

• Investigating the factors contributing to healthy aging and longevity.
• Assessing the impact of dementia and Alzheimer’s disease on elderly individuals and their families.
• Strategies for improving elder care services and addressing the aging population’s healthcare needs.
• Exploring the social isolation and mental health challenges faced by the elderly.
• The importance of nutrition and exercise in old age.
• Investigating the impact of age-related chronic diseases, such as arthritis and osteoporosis.
• Assessing the financial and ethical aspects of end-of-life care for the elderly.
• Strategies for promoting intergenerational relationships and support networks.
• The influence of cultural differences on aging and health outcomes.
• Exploring technology and innovation in elder care, including assistive devices and telemedicine.

Health Technology and Innovation Research Topics

• The impact of telemedicine and virtual health platforms on patient care and outcomes.
• Investigating the use of wearable health technology in monitoring and managing chronic conditions.
• Assessing the ethical and privacy considerations of health data collection through technology.
• Investigating medical diagnoses and treatment with AI and ML.
• The role of robotics in healthcare, including surgical procedures and elder care.
• Investigating the use of 3D printing in healthcare, such as prosthetics and medical devices.
• The influence of mobile health apps on patient engagement and self-care.
• Strategies for implementing electronic health records (EHRs) and interoperability.
• The impact of precision medicine and genomics on personalized healthcare.
• Exploring the future of healthcare delivery through telehealth, remote monitoring, and AI-driven diagnostics.

Global Health Research Topics

• Investigating the challenges of global health equity and healthcare access in low- and middle-income countries.
• Assessing the effectiveness of international health organizations in addressing global health crises.
• Resource-limited mother and child health strategies.
• Exploring the impact of infectious diseases in global health, including tuberculosis and HIV/AIDS.
• The role of clean water and sanitation in improving global health outcomes.
• Investigating the social determinants of health in different global regions.
• Assessing the impact of humanitarian aid and disaster relief efforts on public health.
• Strategies for combating malnutrition and food insecurity in developing countries.
• The influence of climate change on global health, including the spread of vector-borne diseases.
• Exploring innovative approaches to global health, such as community health workers and telemedicine initiatives.
• Exploring the artificial intelligence and machine learning in medical treatment.

Health Disparities and Equity Research Topics

• The impact of socioeconomic status on healthcare access and health outcomes.
• Strategies to decrease racial and ethnic disparities in maternal and child health.
• LGBTQ+ healthcare disparities and interventions for equitable care.
• Health disparities among rural and urban populations in developed and developing countries.
• Cultural competence in healthcare and its role in reducing disparities.
• The intersection of gender, race, and socioeconomic status in health disparities.
• Addressing health disparities in the elderly population.
• The role of discrimination in perpetuating health inequities.
• Strategies to improve healthcare access for individuals with disabilities.
• The impact of COVID-19 on health disparities and lessons learned for future pandemics.

Cancer Research Topics

• Advancements in precision medicine for personalized cancer treatment.
• Immunotherapy breakthroughs in cancer treatment.
• Environmental factors and cancer risk: A comprehensive review.
• The role of genomics in understanding cancer susceptibility.
• Cancer treatment and survivorship, as well as quality of life following cancer therapy.
• The economics of cancer treatment and its impact on patients.
• Cancer prevention and early detection strategies in underserved communities.
• Palliative care and end-of-life decisions in cancer patients.
• Emerging trends in cancer epidemiology and global burden.
• Ethical considerations in cancer clinical trials and research.

Pharmaceutical Research Topics

• Repurposing existing medications in order to address uncommon illnesses.
• The impact of nanotechnology in drug delivery and targeting.
• Pharmacogenomics and personalized medicine: Current status and future prospects.
• Challenges and opportunities in developing vaccines for emerging infectious diseases.
• Quality control and safety in the pharmaceutical manufacturing process.
• Drug pricing and access: A global perspective.
• Green chemistry approaches in sustainable pharmaceutical development.
• The part that artificial intelligence plays in the search for new drugs and their development.
• Biopharmaceuticals and the future of protein-based therapies.
• Regulatory challenges in ensuring drug safety and efficacy.

Epidemiology Research Topics

• Emerging infectious diseases and global preparedness.
• The COVID-19 pandemic will have long-term effect on the health of the general population.
• Social determinants of health and their impact on disease prevalence.
• Environmental epidemiology and the study of health effects of pollution.
• Big data and its role in modern epidemiological research.
• Spatial epidemiology and the study of disease clusters.
• Epidemiological aspects of non-communicable diseases (NCDs) like diabetes and obesity.
• Genetic epidemiology and the study of hereditary diseases.
• Epidemiological methods for studying mental health disorders.
• Epidemiology of zoonotic diseases and their prevention.

Alternative and Complementary Medicine Research Topics

• Efficacy and safety of herbal remedies in complementary medicine.
• Mind-body interventions and their role in managing chronic pain.
• Acupuncture and its potential in the treatment of various conditions.
• Integrating traditional and complementary medicine into mainstream healthcare.
• Yoga and meditation for stress reduction and mental health.
• Biofield therapies and their impact on well-being.
• Ayurvedic medicine and its modern applications in health and wellness.
• Chiropractic care and its use in musculoskeletal health.
• Ethical considerations in the practice and regulation of alternative medicine.
• Integrating traditional Chinese medicine into Western healthcare systems.

Occupational Health and Safety Research Topics

• Occupational hazards in healthcare settings and strategies for prevention.
• The impact of remote work on occupational health and well-being.
• Ergonomics and its role in preventing workplace injuries.
• Occupational exposure to hazardous chemicals and long-term health effects.
• Mental health in the office: Stress, burnout, and interventions.
• Occupational safety in the construction industry: Recent developments.
• Role of technology in enhancing workplace safety.
• Occupational health disparities among different industries and occupations.
• The economics of workplace safety and the cost-benefit analysis.
• Business impacts of OSHA regulations.

Addiction and Substance Abuse Research Topics

• The opioid epidemic: Current status and future strategies.
• Dual diagnosis: Co-occurring mental health disorders and substance abuse.
• Harm reduction approaches in addiction treatment.
• The role of family and social support in addiction recovery.
• Behavioral addictions: Understanding and treating non-substance-related addictions.
• Novel pharmacotherapies for addiction treatment.
• The impact of COVID-19 on substance abuse and addiction.
• Substance abuse prevention programs in schools and communities.
• Stigmatization of addiction and its impact on treatment-seeking behavior.
• Substance abuse in the elderly population: Unique challenges and solutions.

Biomedical Research Topics

• Recent advancements in gene editing technologies (e.g., CRISPR-Cas9).
• Regenerative medicine and tissue engineering for organ replacement.
• Bioinformatics and its role in analyzing large-scale biological data.
• Stem cell research and its important applications in regenerative medicine.
• Biomarker discovery for early disease detection and monitoring.
• Precision medicine and its potential to transform healthcare.
• The microbiome and its impacts on human health and disease.
• Aging-related research and interventions for healthy aging.
• Neurodegenerative diseases and potential therapeutic approaches.
• Biomedical ethics in the age of cutting-edge research.

Maternal and Child Health Research Topics

• The influence of the mother’s nutrition on the development and health of the fetus.
• Maternal mental health and its positive effects on child development.
• Preterm birth prevention and interventions for at-risk pregnancies.
• Neonatal screening and early diagnosis of congenital diseases.
• Breastfeeding promotion and support for new mothers.
• Pediatric immunization programs and vaccine hesitancy.
• Child obesity prevention and intervention strategies.
• Maternal and child health in low-resource and conflict-affected areas.
• Maternal mortality reduction and improving access to obstetric care.
• Adverse childhood experiences (ACEs) and their long-term health consequences.

Mental Health Stigma Research Topics

• Understanding the origins and perpetuation of mental health stigma.
• Media and pop culture’s impact on mental disease views.
• Reducing stigma in the workplace and promoting mental health support.
• Stigma associated with specific mental health conditions (e.g., schizophrenia, bipolar disorder).
• Intersectionality and how it influences mental health stigma.
• Anti-stigma campaigns and their effectiveness in changing public attitudes.
• Stigma in online communities and the role of social media in shaping opinions.
• Cultural and cross-cultural perspectives on mental health stigma.
• The impact of self-stigma on individuals seeking mental health treatment.
• Legislative and policy efforts to combat mental health stigma.

Health Education and Promotion Research Topics

• Health literacy and its impact on informed decision-making.
• Promoting healthy behaviors in schools and educational settings.
• Social marketing campaigns for health behavior change.
• Community-based health promotion programs in underserved areas.
• The role of technology and social media in health education.
• Tailoring health messages to diverse populations and cultural sensitivity.
• The use of behavioral economics in health promotion strategies.
• Investigating the effectiveness of school-based sex education programs.
• Health education for the elderly population: Challenges and solutions.
• Promoting mental health awareness and resilience through education.

Healthcare Quality and Patient Safety Research Topics

• Patient-centered care and its impact on healthcare quality.
• Reducing medical errors and negative events in healthcare settings.
• Continuous quality improvement in healthcare organizations.
• The role of healthcare accreditation in ensuring quality and safety.
• Patient engagement and shared decision-making in healthcare.
• Electronic health records and patient safety.
• The ethics of telling patients and families about medical blunders.
• Medication safety and preventing adverse drug events.
• Cultural competence in healthcare and its effect on patient safety.
• Disaster preparedness and response in healthcare settings.

Health Informatics and Data Analytics Research Topics

• Big data analytics in healthcare for predictive modeling.
• Artificial intelligence in medical image analysis and diagnostics.
• Health information exchange and interoperability challenges.
• Electronic health record (EHR) usability and user satisfaction.
• Patient data privacy and security in health informatics.
• Telemedicine and its impact on healthcare delivery and data management.
• Real-time monitoring and data analytics for disease outbreaks.
• Health informatics applications in personalized medicine.
• Natural language processing for clinical notes and text analysis.
• The role of data analyticsin enhancing healthcare quality and outcomes.

Neurological Disorders Research Topics

• Neuroinflammation in neurodegenerative diseases (e.g., Alzheimer’s and Parkinson’s).
• Stroke prevention and rehabilitation strategies.
• Advances in brain imaging techniques for diagnosing neurological disorders.
• Pediatric neurological disorders: Diagnosis and intervention.
• Neurogenetics and the role of genetics in neurological conditions.
• Traumatic brain injury: Long-term effects and rehabilitation.
• Neurorehabilitation and quality of life improvement in patients with neurological disorders.
• Neurological consequences of long COVID and post-viral syndromes.
• The gut-brain connection and its implications for neurological health.
• Ethical considerations in neurological research and treatment.

Bioethics in Health Research Topics

• Informed consent and its challenges in clinical trials and research.
• Ethical considerations in human genome editing and gene therapy.
• Allocation of healthcare resources and the principles of distributive justice.
• The ethics of organ transplantation and organ trafficking.
• End-of-life decision-making, including physician-assisted suicide.
• Ethical issues in the use of Artficial intelligence in healthcare decision-making.
• Research involving vulnerable populations: Balancing benefits and risks.
• Ethical considerations in global health research and disparities.
• Ethical implications of emerging biotechnologies, such as CRISPR-Cas9.
• Autonomy and decision-making capacity in healthcare ethics.

Read More 

• Biology Research Topics
• Neuroscience Research Topics

Points To Be Remembered While Selecting Health Related Research Topics

When selecting a health-related research topic, there are several important considerations to keep in mind to ensure your research is meaningful and effective. Here are 7 key points to remember:

• Interest and Passion: Choose a topic that is according to your interests you, as your enthusiasm will fuel your research.
• Relevance: Ensure your topic addresses a real health issue or concern that can make a positive impact.
• Resources Availability: Confirm that you have access to the necessary materials and information for your research.
• Manageability: Pick a topic that is not too broad, ensuring it’s something you can investigate thoroughly.
• Guidance: Seek advice from experts or mentors to refine your topic and receive valuable insights.
• Ethical Considerations : Always consider the ethical implications of your research and ensure it complies with ethical guidelines.
• Feasibility: Ensure that the research can be completed within the available time and resources.

In the ever-evolving landscape of health research, selecting the right topic is the foundation for meaningful contributions. This blog has provided a roadmap for choosing health-related research topics, emphasizing the importance of personal interest, relevance, available resources, manageability, and expert guidance. Additionally, it has offered 300+ research topics across various domains, including mental health, public health, nutrition, chronic diseases, healthcare policy, and more. 

In addition, with these insights, researchers, students, and healthcare professionals can embark on journeys that not only align with their passions but also address critical healthcare challenges. By making informed choices, we can collectively advance the frontiers of health and well-being.

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55 research questions about mental health

Last updated

11 March 2024

Reviewed by

Brittany Ferri, PhD, OTR/L

Short on time? Get an AI generated summary of this article instead

Research in the mental health space helps fill knowledge gaps and create a fuller picture for patients, healthcare professionals, and policymakers. Over time, these efforts result in better quality care and more accessible treatment options for those who need them.

Use this list of mental health research questions to kickstart your next project or assignment and give yourself the best chance of producing successful and fulfilling research.

• Why does mental health research matter?

Mental health research is an essential area of study. It includes any research that focuses on topics related to people’s mental and emotional well-being.

As a complex health topic that, despite the prevalence of mental health conditions, still has an unending number of unanswered questions, the need for thorough research into causes, triggers, and treatment options is clear.

Research into this heavily stigmatized and often misunderstood topic is needed to find better ways to support people struggling with mental health conditions. Understanding what causes them is another crucial area of study, as it enables individuals, companies, and policymakers to make well-informed choices that can help prevent illnesses like anxiety and depression.

• How to choose a strong mental health research topic

As one of the most important parts of beginning a new research project, picking a topic that is intriguing, unique, and in demand is a great way to get the best results from your efforts.

Mental health is a blanket term with many niches and specific areas to explore. But, no matter which direction you choose, follow the tips below to ensure you pick the right topic.

Prioritize your interests and skills

While a big part of research is exploring a new and exciting topic, this exploration is best done within a topic or niche in which you are interested and experienced.

Research is tough, even at the best of times. To combat fatigue and increase your chances of pushing through to the finish line, we recommend choosing a topic that aligns with your personal interests, training, or skill set.

Consider emerging trends

Topical and current research questions are hot commodities because they offer solutions and insights into culturally and socially relevant problems.

Depending on the scope and level of freedom you have with your upcoming research project, choosing a topic that’s trending in your area of study is one way to get support and funding (if you need it).

Not every study can be based on a cutting-edge topic, but this can be a great way to explore a new space and create baseline research data for future studies.

Assess your resources and timeline

Before choosing a super ambitious and exciting research topic, consider your project restrictions.

You’ll need to think about things like your research timeline, access to resources and funding, and expected project scope when deciding how broad your research topic will be. In most cases, it’s better to start small and focus on a specific area of study.

Broad research projects are expensive and labor and resource-intensive. They can take years or even decades to complete. Before biting off more than you can chew, consider your scope and find a research question that fits within it.

Read up on the latest research

Finally, once you have narrowed in on a specific topic, you need to read up on the latest studies and published research. A thorough research assessment is a great way to gain some background context on your chosen topic and stops you from repeating a study design. Using the existing work as your guide, you can explore more specific and niche questions to provide highly beneficial answers and insights.

• Trending research questions for post-secondary students

As a post-secondary student, finding interesting research questions that fit within the scope of your classes or resources can be challenging. But, with a little bit of effort and pre-planning, you can find unique mental health research topics that will meet your class or project requirements.

Examples of research topics for post-secondary students include the following:

How does school-related stress impact a person’s mental health?

To what extent does burnout impact mental health in medical students?

How does chronic school stress impact a student’s physical health?

How does exam season affect the severity of mental health symptoms?

Is mental health counseling effective for students in an acute mental crisis?

• Research questions about anxiety and depression

Anxiety and depression are two of the most commonly spoken about mental health conditions. You might assume that research about these conditions has already been exhausted or that it’s no longer in demand. That’s not the case at all.

According to a 2022 survey by Centers for Disease Control and Prevention (CDC), 12.5% of American adults struggle with regular feelings of worry, nervousness, and anxiety, and 5% struggle with regular feelings of depression. These percentages amount to millions of lives affected, meaning new research into these conditions is essential.

If either of these topics interests you, here are a few trending research questions you could consider:

Does gender play a role in the early diagnosis of anxiety?

How does untreated anxiety impact quality of life?

What are the most common symptoms of anxiety in working professionals aged 20–29?

To what extent do treatment delays impact quality of life in patients with undiagnosed anxiety?

To what extent does stigma affect the quality of care received by people with anxiety?

Here are some examples of research questions about depression:

Does diet play a role in the severity of depression symptoms?

Can people have a genetic predisposition to developing depression?

How common is depression in work-from-home employees?

Does mood journaling help manage depression symptoms?

What role does exercise play in the management of depression symptoms?

• Research questions about personality disorders

Personality disorders are complex mental health conditions tied to a person’s behaviors, sense of self, and how they interact with the world around them. Without a diagnosis and treatment, people with personality disorders are more likely to develop negative coping strategies during periods of stress and adversity, which can impact their quality of life and relationships.

There’s no shortage of specific research questions in this category. Here are some examples of research questions about personality disorders that you could explore:

What environments are more likely to trigger the development of a personality disorder?

What barriers impact access to care for people with personality disorders?

To what extent does undiagnosed borderline personality disorder impact a person’s ability to build relationships?

How does group therapy impact symptom severity in people with schizotypal personality disorder?

What is the treatment compliance rate of people with paranoid personality disorder?

• Research questions about substance use disorders

“Substance use disorders” is a blanket term for treatable behaviors and patterns within a person’s brain that lead them to become dependent on illicit drugs, alcohol, or prescription medications. It’s one of the most stigmatized mental health categories.

The severity of a person’s symptoms and how they impact their ability to participate in their regular daily life can vary significantly from person to person. But, even in less severe cases, people with a substance use disorder display some level of loss of control due to their need to use the substance they are dependent on.

This is an ever-evolving topic where research is in hot demand. Here are some example research questions:

To what extent do meditation practices help with craving management?

How effective are detox centers in treating acute substance use disorder?

Are there genetic factors that increase a person’s chances of developing a substance use disorder?

How prevalent are substance use disorders in immigrant populations?

To what extent do prescription medications play a role in developing substance use disorders?

• Research questions about mental health treatments

Treatments for mental health, pharmaceutical therapies in particular, are a common topic for research and exploration in this space.

Besides the clinical trials required for a drug to receive FDA approval, studies into the efficacy, risks, and patient experiences are essential to better understand mental health therapies.

These types of studies can easily become large in scope, but it’s possible to conduct small cohort research on mental health therapies that can provide helpful insights into the actual experiences of the people receiving these treatments.

Here are some questions you might consider:

What are the long-term effects of electroconvulsive therapy (ECT) for patients with severe depression?

How common is insomnia as a side effect of oral mental health medications?

What are the most common causes of non-compliance for mental health treatments?

How long does it take for patients to report noticeable changes in symptom severity after starting injectable mental health medications?

What issues are most common when weaning a patient off of an anxiety medication?

• Controversial mental health research questions

If you’re interested in exploring more cutting-edge research topics, you might consider one that’s “controversial.”

Depending on your own personal values, you might not think many of these topics are controversial. In the context of the research environment, this depends on the perspectives of your project lead and the desires of your sponsors. These topics may not align with the preferred subject matter.

That being said, that doesn’t make them any less worth exploring. In many cases, it makes them more worthwhile, as they encourage people to ask questions and think critically.

Here are just a few examples of “controversial” mental health research questions:

To what extent do financial crises impact mental health in young adults?

How have climate concerns impacted anxiety levels in young adults?

To what extent do psychotropic drugs help patients struggling with anxiety and depression?

To what extent does political reform impact the mental health of LGBTQ+ people?

What mental health supports should be available for the families of people who opt for medically assisted dying?

• Research questions about socioeconomic factors & mental health

Socioeconomic factors—like where a person grew up, their annual income, the communities they are exposed to, and the amount, type, and quality of mental health resources they have access to—significantly impact overall health.

This is a complex and multifaceted issue. Choosing a research question that addresses these topics can help researchers, experts, and policymakers provide more equitable and accessible care over time.

Examples of questions that tackle socioeconomic factors and mental health include the following:

How does sliding scale pricing for therapy increase retention rates?

What is the average cost to access acute mental health crisis care in [a specific region]?

To what extent does a person’s environment impact their risk of developing a mental health condition?

How does mental health stigma impact early detection of mental health conditions?

To what extent does discrimination affect the mental health of LGBTQ+ people?

• Research questions about the benefits of therapy

Therapy, whether that’s in groups or one-to-one sessions, is one of the most commonly utilized resources for managing mental health conditions. It can help support long-term healing and the development of coping mechanisms.

Yet, despite its popularity, more research is needed to properly understand its benefits and limitations.

Here are some therapy-based questions you could consider to inspire your own research:

In what instances does group therapy benefit people more than solo sessions?

How effective is cognitive behavioral therapy for patients with severe anxiety?

After how many therapy sessions do people report feeling a better sense of self?

Does including meditation reminders during therapy improve patient outcomes?

To what extent has virtual therapy improved access to mental health resources in rural areas?

• Research questions about mental health trends in teens

Adolescents are a particularly interesting group for mental health research due to the prevalence of early-onset mental health symptoms in this age group.

As a time of self-discovery and change, puberty brings plenty of stress, anxiety, and hardships, all of which can contribute to worsening mental health symptoms.

If you’re looking to learn more about how to support this age group with mental health, here are some examples of questions you could explore:

Does parenting style impact anxiety rates in teens?

How early should teenagers receive mental health treatment?

To what extent does cyberbullying impact adolescent mental health?

What are the most common harmful coping mechanisms explored by teens?

How have smartphones affected teenagers’ self-worth and sense of self?

• Research questions about social media and mental health

Social media platforms like TikTok, Instagram, YouTube, Facebook, and X (formerly Twitter) have significantly impacted day-to-day communication. However, despite their numerous benefits and uses, they have also become a significant source of stress, anxiety, and self-worth issues for those who use them.

These platforms have been around for a while now, but research on their impact is still in its infancy. Are you interested in building knowledge about this ever-changing topic? Here are some examples of social media research questions you could consider:

To what extent does TikTok’s mental health content impact people’s perception of their health?

How much non-professional mental health content is created on social media platforms?

How has social media content increased the likelihood of a teen self-identifying themselves with ADHD or autism?

To what extent do social media photoshopped images impact body image and self-worth?

Has social media access increased feelings of anxiety and dread in young adults?

• Mental health research is incredibly important

As you have seen, there are so many unique mental health research questions worth exploring. Which options are piquing your interest?

Whether you are a university student considering your next paper topic or a professional looking to explore a new area of study, mental health is an exciting and ever-changing area of research to get involved with.

Your research will be valuable, no matter how big or small. As a niche area of healthcare still shrouded in stigma, any insights you gain into new ways to support, treat, or identify mental health triggers and trends are a net positive for millions of people worldwide.

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Research Topics & Ideas: Public Health

I If you’re just starting out exploring public health and/or epidemiology-related topics for your dissertation, thesis or research project, you’ve come to the right place. In this post, we’ll help kickstart your research by providing a hearty list of research ideas , including examples from recent studies in public health and epidemiology.

PS – This is just the start…

We know it’s exciting to run through a list of research topics, but please keep in mind that this list is just a starting point . These topic ideas provided here are intentionally broad and generic , so keep in mind that you will need to develop them further. Nevertheless, they should inspire some ideas for your project.

To develop a suitable research topic, you’ll need to identify a clear and convincing research gap , and a viable plan to fill that gap. If this sounds foreign to you, check out our free research topic webinar that explores how to find and refine a high-quality research topic, from scratch. Alternatively, consider our 1-on-1 coaching service .

Public Health-Related Research Topics

• Evaluating the impact of community-based obesity prevention programs in urban areas.
• Analyzing the effectiveness of public smoking bans on respiratory health outcomes.
• Investigating the role of health education in reducing the prevalence of HIV/AIDS in sub-Saharan Africa.
• The impact of air pollution on asthma rates in industrial cities.
• Evaluating the effectiveness of school nutrition programs on childhood obesity rates.
• The role of public health policies in addressing mental health stigma.
• Analyzing the impact of clean water access on infectious disease rates in rural communities.
• The effectiveness of needle exchange programs in reducing the spread of hepatitis C.
• Investigating the impact of social determinants on maternal and child health in low-income neighborhoods.
• The role of digital health interventions in managing chronic diseases.
• Analyzing the effectiveness of workplace wellness programs on employee health and productivity.
• The impact of urban green spaces on community mental health.
• Evaluating the effectiveness of vaccination campaigns in preventing outbreaks of infectious diseases.
• The role of public health initiatives in reducing alcohol-related harm.
• Analyzing the impact of aging populations on healthcare systems.
• Analyzing the impact of urbanization on mental health disorders in metropolitan areas.
• The effectiveness of telemedicine services in improving healthcare access in remote regions.
• Investigating the health impacts of electronic waste recycling practices.
• The role of health literacy in managing non-communicable diseases in aging populations.
• Evaluating the public health response to opioid addiction in rural communities.
• Analyzing the relationship between housing quality and respiratory illnesses.
• The effectiveness of community engagement in improving reproductive health services.
• Investigating the health effects of long-term exposure to low-level environmental radiation.
• The role of public health campaigns in reducing the prevalence of tobacco use among teenagers.
• Analyzing the impact of food deserts on nutritional outcomes in urban communities.

Epidemiology Research Ideas (Continued)

• Investigating the epidemiology of antibiotic-resistant infections in hospital settings.
• The impact of climate change on the spread of vector-borne diseases.
• Evaluating the factors contributing to the rise in type 2 diabetes prevalence.
• Analyzing the epidemiology of mental health disorders in conflict zones.
• The role of epidemiological surveillance in pandemic preparedness and response.
• Investigating the link between environmental exposures and the incidence of childhood cancers.
• The impact of dietary patterns on the prevalence of cardiovascular diseases.
• Evaluating the effectiveness of intervention strategies in controlling obesity epidemics.
• Analyzing the spread and control of zoonotic diseases in rural communities.
• The role of genetic factors in the epidemiology of autoimmune diseases.
• Investigating the socio-economic disparities in cancer incidence and outcomes.
• The impact of urbanization on the epidemiology of infectious diseases.
• Evaluating the public health consequences of occupational exposures to hazardous substances.
• Analyzing the trends and determinants of mental health disorders among adolescents.
• The role of lifestyle factors in the epidemiology of neurodegenerative diseases.
• Investigating the patterns of mental health service utilization during economic recessions.
• The epidemiology of sports-related concussions in youth athletics.
• Evaluating the effectiveness of public health interventions in reducing the spread of tuberculosis in high-risk populations.
• Analyzing the geographic distribution of Lyme disease in relation to climate change.
• The role of international travel in the spread of emerging infectious diseases.
• Investigating the demographic predictors of chronic kidney disease in population-based studies.
• The epidemiological impact of air pollution on asthma and other respiratory conditions.
• Evaluating the long-term health effects of exposure to endocrine-disrupting chemicals.
• Analyzing the incidence and risk factors of post-traumatic stress disorder in first responders.
• The role of socioeconomic status in the prevalence and management of diabetes.

Recent Studies: Public Health & Epidemiology

While the ideas we’ve presented above are a decent starting point for finding a research topic, they are fairly generic and non-specific. So, it helps to look at actual studies in the public health and epidemiology space to see how this all comes together in practice.

Below, we’ve included a selection of recent studies to help refine your thinking. These are actual studies,  so they can provide some useful insight as to what a research topic looks like in practice.

• Tutorials in population neuroimaging: Using epidemiology in neuroimaging research (Godina et al., 2022)
• Application of Big Data in Digital Epidemiology (Naaz & Siddiqui, 2022)
• Response to comment on: Incidence of ocular and systemic disease affecting visual function among state bus drivers (Kohli et al., 2022)
• Why epidemiology is incomplete without qualitative and mixed methods (Lane-Fall, 2023)
• Teaching epidemiology: An overview of strategies and considerations (Hossain, 2022)
• Social Epidemiology: Past, Present, and Future (Roux, 2022)
• Population health assessment project: An innovative strategy for teaching principles of epidemiology (Keen et al., 2022)
• The functions of veterinary epidemiology in public health (Shaffi, 2023)
• Readying the Applied Epidemiology Workforce for Emerging Areas of
• Public Health Practice (Daly et al., 2022)
• Some Social Epidemiologic Lessons from the COVID-19 Pandemic (Schnake-Mahl & Bilal, 2023)
• The Filth Disease: Typhoid Fever and the Practices of Epidemiology in Victorian England by Jacob Steere-Williams (review) (Steere-Williams et al., 2022)
• Epidemiology of Adult Obesity, Measurements, Global Prevalence and Risk Factors (Orukwowu, 2022).
• Which disciplines form digital public health, and how do they relate to each other? (Pan, 2022)
• Information Flow and Data Gaps in COVID-19 Recording and Reporting at National and Provincial Levels in Indonesia (Barsasella et al., 2022). Epidemiology Blog of Neal D. Goldstein, PhD, MBI (Goldstein, 2023)
• Sensitivity analysis of SEIR epidemic model of Covid 19 spread in Indonesia (Rangkuti et al., 2022)

As you can see, these research topics are a lot more focused than the generic topic ideas we presented earlier. So, for you to develop a high-quality research topic, you’ll need to get specific and laser-focused on a specific context with specific variables of interest.  In the video below, we explore some other important things you’ll need to consider when crafting your research topic.

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If you’re still unsure about how to find a quality research topic, check out our Research Topic Kickstarter service, which is the perfect starting point for developing a unique, well-justified research topic.

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Research Topics & Ideas: Automation & Robotics

A comprehensive list of automation and robotics-related research topics. Includes free access to a webinar and research topic evaluator.

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A comprehensive list of sociology-related research topics. Includes free access to a webinar and research topic evaluator.

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Qualitative Methods in Health Care Research

Vishnu renjith, renjulal yesodharan, judith a noronha, elissa ladd, anice george.

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Address for correspondence: Dr. Vishnu Renjith, Lecturer, School of Nursing and Midwifery, Royal College of Surgeons Ireland - Bahrain (RCSI Bahrain), P.O. Box15503, Adliya, Bahrain. E-mail: [email protected]

Received 2019 Sep 15; Accepted 2019 Dec 23; Collection date 2021.

This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

Healthcare research is a systematic inquiry intended to generate robust evidence about important issues in the fields of medicine and healthcare. Qualitative research has ample possibilities within the arena of healthcare research. This article aims to inform healthcare professionals regarding qualitative research, its significance, and applicability in the field of healthcare. A wide variety of phenomena that cannot be explained using the quantitative approach can be explored and conveyed using a qualitative method. The major types of qualitative research designs are narrative research, phenomenological research, grounded theory research, ethnographic research, historical research, and case study research. The greatest strength of the qualitative research approach lies in the richness and depth of the healthcare exploration and description it makes. In health research, these methods are considered as the most humanistic and person-centered way of discovering and uncovering thoughts and actions of human beings.

Keywords: Ethnography , grounded theory , qualitative research , research design

Introduction

Healthcare research is a systematic inquiry intended to generate trustworthy evidence about issues in the field of medicine and healthcare. The three principal approaches to health research are the quantitative, the qualitative, and the mixed methods approach. The quantitative research method uses data, which are measures of values and counts and are often described using statistical methods which in turn aids the researcher to draw inferences. Qualitative research incorporates the recording, interpreting, and analyzing of non-numeric data with an attempt to uncover the deeper meanings of human experiences and behaviors. Mixed methods research, the third methodological approach, involves collection and analysis of both qualitative and quantitative information with an objective to solve different but related questions, or at times the same questions.[ 1 , 2 ]

In healthcare, qualitative research is widely used to understand patterns of health behaviors, describe lived experiences, develop behavioral theories, explore healthcare needs, and design interventions.[ 1 , 2 , 3 ] Because of its ample applications in healthcare, there has been a tremendous increase in the number of health research studies undertaken using qualitative methodology.[ 4 , 5 ] This article discusses qualitative research methods, their significance, and applicability in the arena of healthcare.

Qualitative Research

Diverse academic and non-academic disciplines utilize qualitative research as a method of inquiry to understand human behavior and experiences.[ 6 , 7 ] According to Munhall, “Qualitative research involves broadly stated questions about human experiences and realities, studied through sustained contact with the individual in their natural environments and producing rich, descriptive data that will help us to understand those individual's experiences.”[ 8 ]

Significance of Qualitative Research

The qualitative method of inquiry examines the 'how' and 'why' of decision making, rather than the 'when,' 'what,' and 'where.'[ 7 ] Unlike quantitative methods, the objective of qualitative inquiry is to explore, narrate, and explain the phenomena and make sense of the complex reality. Health interventions, explanatory health models, and medical-social theories could be developed as an outcome of qualitative research.[ 9 ] Understanding the richness and complexity of human behavior is the crux of qualitative research.

Differences between Quantitative and Qualitative Research

The quantitative and qualitative forms of inquiry vary based on their underlying objectives. They are in no way opposed to each other; instead, these two methods are like two sides of a coin. The critical differences between quantitative and qualitative research are summarized in Table 1 .[ 1 , 10 , 11 ]

Differences between quantitative and qualitative research

Qualitative Research Questions and Purpose Statements

Qualitative questions are exploratory and are open-ended. A well-formulated study question forms the basis for developing a protocol, guides the selection of design, and data collection methods. Qualitative research questions generally involve two parts, a central question and related subquestions. The central question is directed towards the primary phenomenon under study, whereas the subquestions explore the subareas of focus. It is advised not to have more than five to seven subquestions. A commonly used framework for designing a qualitative research question is the 'PCO framework' wherein, P stands for the population under study, C stands for the context of exploration, and O stands for the outcome/s of interest.[ 12 ] The PCO framework guides researchers in crafting a focused study question.

Example: In the question, “What are the experiences of mothers on parenting children with Thalassemia?”, the population is “mothers of children with Thalassemia,” the context is “parenting children with Thalassemia,” and the outcome of interest is “experiences.”

The purpose statement specifies the broad focus of the study, identifies the approach, and provides direction for the overall goal of the study. The major components of a purpose statement include the central phenomenon under investigation, the study design and the population of interest. Qualitative research does not require a-priori hypothesis.[ 13 , 14 , 15 ]

Example: Borimnejad et al . undertook a qualitative research on the lived experiences of women suffering from vitiligo. The purpose of this study was, “to explore lived experiences of women suffering from vitiligo using a hermeneutic phenomenological approach.” [ 16 ]

Review of the Literature

In quantitative research, the researchers do an extensive review of scientific literature prior to the commencement of the study. However, in qualitative research, only a minimal literature search is conducted at the beginning of the study. This is to ensure that the researcher is not influenced by the existing understanding of the phenomenon under the study. The minimal literature review will help the researchers to avoid the conceptual pollution of the phenomenon being studied. Nonetheless, an extensive review of the literature is conducted after data collection and analysis.[ 15 ]

Reflexivity

Reflexivity refers to critical self-appraisal about one's own biases, values, preferences, and preconceptions about the phenomenon under investigation. Maintaining a reflexive diary/journal is a widely recognized way to foster reflexivity. According to Creswell, “Reflexivity increases the credibility of the study by enhancing more neutral interpretations.”[ 7 ]

Types of Qualitative Research Designs

The qualitative research approach encompasses a wide array of research designs. The words such as types, traditions, designs, strategies of inquiry, varieties, and methods are used interchangeably. The major types of qualitative research designs are narrative research, phenomenological research, grounded theory research, ethnographic research, historical research, and case study research.[ 1 , 7 , 10 ]

Narrative research

Narrative research focuses on exploring the life of an individual and is ideally suited to tell the stories of individual experiences.[ 17 ] The purpose of narrative research is to utilize 'story telling' as a method in communicating an individual's experience to a larger audience.[ 18 ] The roots of narrative inquiry extend to humanities including anthropology, literature, psychology, education, history, and sociology. Narrative research encompasses the study of individual experiences and learning the significance of those experiences. The data collection procedures include mainly interviews, field notes, letters, photographs, diaries, and documents collected from one or more individuals. Data analysis involves the analysis of the stories or experiences through “re-storying of stories” and developing themes usually in chronological order of events. Rolls and Payne argued that narrative research is a valuable approach in health care research, to gain deeper insight into patient's experiences.[ 19 ]

Example: Karlsson et al . undertook a narrative inquiry to “explore how people with Alzheimer's disease present their life story.” Data were collected from nine participants. They were asked to describe about their life experiences from childhood to adulthood, then to current life and their views about the future life. [ 20 ]

Phenomenological research

Phenomenology is a philosophical tradition developed by German philosopher Edmond Husserl. His student Martin Heidegger did further developments in this methodology. It defines the 'essence' of individual's experiences regarding a certain phenomenon.[ 1 ] The methodology has its origin from philosophy, psychology, and education. The purpose of qualitative research is to understand the people's everyday life experiences and reduce it into the central meaning or the 'essence of the experience'.[ 21 , 22 ] The unit of analysis of phenomenology is the individuals who have had similar experiences of the phenomenon. Interviews with individuals are mainly considered for the data collection, though, documents and observations are also useful. Data analysis includes identification of significant meaning elements, textural description (what was experienced), structural description (how was it experienced), and description of 'essence' of experience.[ 1 , 7 , 21 ] The phenomenological approach is further divided into descriptive and interpretive phenomenology. Descriptive phenomenology focuses on the understanding of the essence of experiences and is best suited in situations that need to describe the lived phenomenon. Hermeneutic phenomenology or Interpretive phenomenology moves beyond the description to uncover the meanings that are not explicitly evident. The researcher tries to interpret the phenomenon, based on their judgment rather than just describing it.[ 7 , 21 , 22 , 23 , 24 ]

Example: A phenomenological study conducted by Cornelio et al . aimed at describing the lived experiences of mothers in parenting children with leukemia. Data from ten mothers were collected using in-depth semi-structured interviews and were analyzed using Husserl's method of phenomenology. Themes such as “pivotal moment in life”, “the experience of being with a seriously ill child”, “having to keep distance with the relatives”, “overcoming the financial and social commitments”, “responding to challenges”, “experience of faith as being key to survival”, “health concerns of the present and future”, and “optimism” were derived. The researchers reported the essence of the study as “chronic illness such as leukemia in children results in a negative impact on the child and on the mother.” [ 25 ]

Grounded Theory Research

Grounded theory has its base in sociology and propagated by two sociologists, Barney Glaser, and Anselm Strauss.[ 26 ] The primary purpose of grounded theory is to discover or generate theory in the context of the social process being studied. The major difference between grounded theory and other approaches lies in its emphasis on theory generation and development. The name grounded theory comes from its ability to induce a theory grounded in the reality of study participants.[ 7 , 27 ] Data collection in grounded theory research involves recording interviews from many individuals until data saturation. Constant comparative analysis, theoretical sampling, theoretical coding, and theoretical saturation are unique features of grounded theory research.[ 26 , 27 , 28 ] Data analysis includes analyzing data through 'open coding,' 'axial coding,' and 'selective coding.'[ 1 , 7 ] Open coding is the first level of abstraction, and it refers to the creation of a broad initial range of categories, axial coding is the procedure of understanding connections between the open codes, whereas selective coding relates to the process of connecting the axial codes to formulate a theory.[ 1 , 7 ] Results of the grounded theory analysis are supplemented with a visual representation of major constructs usually in the form of flow charts or framework diagrams. Quotations from the participants are used in a supportive capacity to substantiate the findings. Strauss and Corbin highlights that “the value of the grounded theory lies not only in its ability to generate a theory but also to ground that theory in the data.”[ 27 ]

Example: Williams et al . conducted a grounded theory research to explore the nature of relationship between the sense of self and the eating disorders. Data were collected form 11 women with a lifetime history of Anorexia Nervosa and were analyzed using the grounded theory methodology. Analysis led to the development of a theoretical framework on the nature of the relationship between the self and Anorexia Nervosa. [ 29 ]

Ethnographic research

Ethnography has its base in anthropology, where the anthropologists used it for understanding the culture-specific knowledge and behaviors. In health sciences research, ethnography focuses on narrating and interpreting the health behaviors of a culture-sharing group. 'Culture-sharing group' in an ethnography represents any 'group of people who share common meanings, customs or experiences.' In health research, it could be a group of physicians working in rural care, a group of medical students, or it could be a group of patients who receive home-based rehabilitation. To understand the cultural patterns, researchers primarily observe the individuals or group of individuals for a prolonged period of time.[ 1 , 7 , 30 ] The scope of ethnography can be broad or narrow depending on the aim. The study of more general cultural groups is termed as macro-ethnography, whereas micro-ethnography focuses on more narrowly defined cultures. Ethnography is usually conducted in a single setting. Ethnographers collect data using a variety of methods such as observation, interviews, audio-video records, and document reviews. A written report includes a detailed description of the culture sharing group with emic and etic perspectives. When the researcher reports the views of the participants it is called emic perspectives and when the researcher reports his or her views about the culture, the term is called etic.[ 7 ]

Example: The aim of the ethnographic study by LeBaron et al . was to explore the barriers to opioid availability and cancer pain management in India. The researchers collected data from fifty-nine participants using in-depth semi-structured interviews, participant observation, and document review. The researchers identified significant barriers by open coding and thematic analysis of the formal interview. [ 31 ]

Historical research

Historical research is the “systematic collection, critical evaluation, and interpretation of historical evidence”.[ 1 ] The purpose of historical research is to gain insights from the past and involves interpreting past events in the light of the present. The data for historical research are usually collected from primary and secondary sources. The primary source mainly includes diaries, first hand information, and writings. The secondary sources are textbooks, newspapers, second or third-hand accounts of historical events and medical/legal documents. The data gathered from these various sources are synthesized and reported as biographical narratives or developmental perspectives in chronological order. The ideas are interpreted in terms of the historical context and significance. The written report describes 'what happened', 'how it happened', 'why it happened', and its significance and implications to current clinical practice.[ 1 , 10 ]

Example: Lubold (2019) analyzed the breastfeeding trends in three countries (Sweden, Ireland, and the United States) using a historical qualitative method. Through analysis of historical data, the researcher found that strong family policies, adherence to international recommendations and adoption of baby-friendly hospital initiative could greatly enhance the breastfeeding rates. [ 32 ]

Case study research

Case study research focuses on the description and in-depth analysis of the case(s) or issues illustrated by the case(s). The design has its origin from psychology, law, and medicine. Case studies are best suited for the understanding of case(s), thus reducing the unit of analysis into studying an event, a program, an activity or an illness. Observations, one to one interviews, artifacts, and documents are used for collecting the data, and the analysis is done through the description of the case. From this, themes and cross-case themes are derived. A written case study report includes a detailed description of one or more cases.[ 7 , 10 ]

Example: Perceptions of poststroke sexuality in a woman of childbearing age was explored using a qualitative case study approach by Beal and Millenbrunch. Semi structured interview was conducted with a 36- year mother of two children with a history of Acute ischemic stroke. The data were analyzed using an inductive approach. The authors concluded that “stroke during childbearing years may affect a woman's perception of herself as a sexual being and her ability to carry out gender roles”. [ 33 ]

Sampling in Qualitative Research

Qualitative researchers widely use non-probability sampling techniques such as purposive sampling, convenience sampling, quota sampling, snowball sampling, homogeneous sampling, maximum variation sampling, extreme (deviant) case sampling, typical case sampling, and intensity sampling. The selection of a sampling technique depends on the nature and needs of the study.[ 34 , 35 , 36 , 37 , 38 , 39 , 40 ] The four widely used sampling techniques are convenience sampling, purposive sampling, snowball sampling, and intensity sampling.

Convenience sampling

It is otherwise called accidental sampling, where the researchers collect data from the subjects who are selected based on accessibility, geographical proximity, ease, speed, and or low cost.[ 34 ] Convenience sampling offers a significant benefit of convenience but often accompanies the issues of sample representation.

Purposive sampling

Purposive or purposeful sampling is a widely used sampling technique.[ 35 ] It involves identifying a population based on already established sampling criteria and then selecting subjects who fulfill that criteria to increase the credibility. However, choosing information-rich cases is the key to determine the power and logic of purposive sampling in a qualitative study.[ 1 ]

Snowball sampling

The method is also known as 'chain referral sampling' or 'network sampling.' The sampling starts by having a few initial participants, and the researcher relies on these early participants to identify additional study participants. It is best adopted when the researcher wishes to study the stigmatized group, or in cases, where findings of participants are likely to be difficult by ordinary means. Respondent ridden sampling is an improvised version of snowball sampling used to find out the participant from a hard-to-find or hard-to-study population.[ 37 , 38 ]

Intensity sampling

The process of identifying information-rich cases that manifest the phenomenon of interest is referred to as intensity sampling. It requires prior information, and considerable judgment about the phenomenon of interest and the researcher should do some preliminary investigations to determine the nature of the variation. Intensity sampling will be done once the researcher identifies the variation across the cases (extreme, average and intense) and picks the intense cases from them.[ 40 ]

Deciding the Sample Size

A-priori sample size calculation is not undertaken in the case of qualitative research. Researchers collect the data from as many participants as possible until they reach the point of data saturation. Data saturation or the point of redundancy is the stage where the researcher no longer sees or hears any new information. Data saturation gives the idea that the researcher has captured all possible information about the phenomenon of interest. Since no further information is being uncovered as redundancy is achieved, at this point the data collection can be stopped. The objective here is to get an overall picture of the chronicle of the phenomenon under the study rather than generalization.[ 1 , 7 , 41 ]

Data Collection in Qualitative Research

The various strategies used for data collection in qualitative research includes in-depth interviews (individual or group), focus group discussions (FGDs), participant observation, narrative life history, document analysis, audio materials, videos or video footage, text analysis, and simple observation. Among all these, the three popular methods are the FGDs, one to one in-depth interviews and the participant observation.

FGDs are useful in eliciting data from a group of individuals. They are normally built around a specific topic and are considered as the best approach to gather data on an entire range of responses to a topic.[ 42 Group size in an FGD ranges from 6 to 12. Depending upon the nature of participants, FGDs could be homogeneous or heterogeneous.[ 1 , 14 ] One to one in-depth interviews are best suited to obtain individuals' life histories, lived experiences, perceptions, and views, particularly while exporting topics of sensitive nature. In-depth interviews can be structured, unstructured, or semi-structured. However, semi-structured interviews are widely used in qualitative research. Participant observations are suitable for gathering data regarding naturally occurring behaviors.[ 1 ]

Data Analysis in Qualitative Research

Various strategies are employed by researchers to analyze data in qualitative research. Data analytic strategies differ according to the type of inquiry. A general content analysis approach is described herewith. Data analysis begins by transcription of the interview data. The researcher carefully reads data and gets a sense of the whole. Once the researcher is familiarized with the data, the researcher strives to identify small meaning units called the 'codes.' The codes are then grouped based on their shared concepts to form the primary categories. Based on the relationship between the primary categories, they are then clustered into secondary categories. The next step involves the identification of themes and interpretation to make meaning out of data. In the results section of the manuscript, the researcher describes the key findings/themes that emerged. The themes can be supported by participants' quotes. The analytical framework used should be explained in sufficient detail, and the analytic framework must be well referenced. The study findings are usually represented in a schematic form for better conceptualization.[ 1 , 7 ] Even though the overall analytical process remains the same across different qualitative designs, each design such as phenomenology, ethnography, and grounded theory has design specific analytical procedures, the details of which are out of the scope of this article.

Computer-Assisted Qualitative Data Analysis Software (CAQDAS)

Until recently, qualitative analysis was done either manually or with the help of a spreadsheet application. Currently, there are various software programs available which aid researchers to manage qualitative data. CAQDAS is basically data management tools and cannot analyze the qualitative data as it lacks the ability to think, reflect, and conceptualize. Nonetheless, CAQDAS helps researchers to manage, shape, and make sense of unstructured information. Open Code, MAXQDA, NVivo, Atlas.ti, and Hyper Research are some of the widely used qualitative data analysis software.[ 14 , 43 ]

Reporting Guidelines

Consolidated Criteria for Reporting Qualitative Research (COREQ) is the widely used reporting guideline for qualitative research. This 32-item checklist assists researchers in reporting all the major aspects related to the study. The three major domains of COREQ are the 'research team and reflexivity', 'study design', and 'analysis and findings'.[ 44 , 45 ]

Critical Appraisal of Qualitative Research

Various scales are available to critical appraisal of qualitative research. The widely used one is the Critical Appraisal Skills Program (CASP) Qualitative Checklist developed by CASP network, UK. This 10-item checklist evaluates the quality of the study under areas such as aims, methodology, research design, ethical considerations, data collection, data analysis, and findings.[ 46 ]

Ethical Issues in Qualitative Research

A qualitative study must be undertaken by grounding it in the principles of bioethics such as beneficence, non-maleficence, autonomy, and justice. Protecting the participants is of utmost importance, and the greatest care has to be taken while collecting data from a vulnerable research population. The researcher must respect individuals, families, and communities and must make sure that the participants are not identifiable by their quotations that the researchers include when publishing the data. Consent for audio/video recordings must be obtained. Approval to be in FGDs must be obtained from the participants. Researchers must ensure the confidentiality and anonymity of the transcripts/audio-video records/photographs/other data collected as a part of the study. The researchers must confirm their role as advocates and proceed in the best interest of all participants.[ 42 , 47 , 48 ]

Rigor in Qualitative Research

The demonstration of rigor or quality in the conduct of the study is essential for every research method. However, the criteria used to evaluate the rigor of quantitative studies are not be appropriate for qualitative methods. Lincoln and Guba (1985) first outlined the criteria for evaluating the qualitative research often referred to as “standards of trustworthiness of qualitative research”.[ 49 ] The four components of the criteria are credibility, transferability, dependability, and confirmability.

Credibility refers to confidence in the 'truth value' of the data and its interpretation. It is used to establish that the findings are true, credible and believable. Credibility is similar to the internal validity in quantitative research.[ 1 , 50 , 51 ] The second criterion to establish the trustworthiness of the qualitative research is transferability, Transferability refers to the degree to which the qualitative results are applicability to other settings, population or contexts. This is analogous to the external validity in quantitative research.[ 1 , 50 , 51 ] Lincoln and Guba recommend authors provide enough details so that the users will be able to evaluate the applicability of data in other contexts.[ 49 ] The criterion of dependability refers to the assumption of repeatability or replicability of the study findings and is similar to that of reliability in quantitative research. The dependability question is 'Whether the study findings be repeated of the study is replicated with the same (similar) cohort of participants, data coders, and context?'[ 1 , 50 , 51 ] Confirmability, the fourth criteria is analogous to the objectivity of the study and refers the degree to which the study findings could be confirmed or corroborated by others. To ensure confirmability the data should directly reflect the participants' experiences and not the bias, motivations, or imaginations of the inquirer.[ 1 , 50 , 51 ] Qualitative researchers should ensure that the study is conducted with enough rigor and should report the measures undertaken to enhance the trustworthiness of the study.

Conclusions

Qualitative research studies are being widely acknowledged and recognized in health care practice. This overview illustrates various qualitative methods and shows how these methods can be used to generate evidence that informs clinical practice. Qualitative research helps to understand the patterns of health behaviors, describe illness experiences, design health interventions, and develop healthcare theories. The ultimate strength of the qualitative research approach lies in the richness of the data and the descriptions and depth of exploration it makes. Hence, qualitative methods are considered as the most humanistic and person-centered way of discovering and uncovering thoughts and actions of human beings.

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Conflicts of interest.

There are no conflicts of interest.

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Defining the Question: Foreground & Background Questions

In order to most appropriately choose an information resource and craft a search strategy, it is necessary to consider what  kind  of question you are asking: a specific, narrow "foreground" question, or a broader background question that will help give context to your research?

Foreground Questions

A "foreground" question in health research is one that is relatively specific, and is usually best addressed by locating primary research evidence. 

Using a structured question framework can help you clearly define the concepts or variables that make up the specific research question. 

 Across most frameworks, you’ll often be considering:

• a who (who was studied - a population or sample)
• a what (what was done or examined - an intervention, an exposure, a policy, a program, a phenomenon)
• a how ([how] did the [what] affect the [who] - an outcome, an effect). 

PICO is the most common framework for developing a clinical research question, but multiple question frameworks exist.

PICO (Problem/Population, Intervention, Comparison, Outcome)

Appropriate for : clinical questions, often addressing the effect of an intervention/therapy/treatment

Example : For adolescents with type II diabetes (P) does the use of telehealth consultations (I) compared to in-person consultations  (C) improve blood sugar control  (O)?

Framing Different Types of Clinical Questions with PICO

Different types of clinical questions are suited to different syntaxes and phrasings, but all will clearly define the PICO elements.  The definitions and frames below may be helpful for organizing your question:

Intervention/Therapy

Questions addressing how a clinical issue, illness, or disability is treated.

"In__________________(P), how does__________________(I) compared to_________________(C) affect______________(O)?"

Questions that address the causes or origin of disease, the factors which produce or predispose toward a certain disease or disorder.

"Are_________________(P), who have_________________(I) compared with those without_________________(C) at_________________risk for/of_________________(O) over_________________(T)?" 

Questions addressing the act or process of identifying or determining the nature and cause of a disease or injury through evaluation.

In_________________(P) are/is_________________(I) compared with_________________(C) more accurate in diagnosing_________________(O)?

Prognosis/Prediction:

Questions addressing the prediction of the course of a disease.

In_________________(P), how does_________________(I) compared to_________________ (C) influence_________________(O)?

Questions addressing how one experiences a phenomenon or why we need to approach practice differently.

"How do_________________(P) with_________________(I) perceive_________________(O)?" 

Adapted from: Melnyk, B. M., & Fineout-Overholt, E. (2011). Evidence-based practice in nursing & healthcare: A guide to best practice. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins.

Beyond PICO: Other Types of Question Frameworks

PICO is a useful framework for clinical research questions, but may not be appropriate for all kinds of reviews.  Also consider:

PEO (Population, Exposure, Outcome)

Appropriate for : describing association between particular exposures/risk factors and outcomes

Example : How do  preparation programs (E) influence the development of teaching competence  (O) among novice nurse educators  (P)?

SPIDER (Sample, Phenomenon of Interest, Design, Evaluation, Research Type)

Appropriate for : questions of experience or perspectives (questions that may be addressed by qualitative or mixed methods research)

Example : What are the experiences and perspectives (E) of  undergraduate nursing students  (S)  in clinical placements within prison healthcare settings (PI)?

SPICE (Setting, Perspective, Intervention/phenomenon of Interest, Comparison, Evaluation)

Appropriate for : evaluating the outcomes of a service, project, or intervention

Example : What are the impacts and best practices for workplace (S) transition support programs (I) for the retention (E) of newly-hired, new graduate nurses (P)?

PCC (Problem/population, Concept, Context)

Appropriate for : broader (scoping) questions

Example : How do nursing schools  (Context) teach, measure, and maintain nursing students ' (P)  technological literacy  (Concept))throughout their educational programs?

Background Questions

To craft a strong and reasonable foreground research question, it is important to have a firm understanding of the concepts of interest.  As such, it is often necessary to ask background questions, which ask for more general, foundational knowledge about a disorder, disease, patient population, policy issue, etc. 

For example, consider the PICO question outlined above:

"For adolescents with type II diabetes does the use of telehealth consultations compared to in-person consultations  improve blood sugar control ?

To best make sense of the literature that might address this PICO question, you would also need a deep understanding of background questions like:

• What are the unique barriers or challenges related to blood sugar management in adolescents with TII diabetes?
• What are the measures of effective blood sugar control?
• What kinds of interventions would fall under the umbrella of 'telehealth'?
• What are the qualitative differences in patient experience in telehealth versus in-person interactions with healthcare providers?
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